Evidence map›Paper›PMID 29582492›Full record

ReviewCell proliferation2018

Long non-coding RNAs in melanoma.

Xin Yu, Heyi Zheng, Gary Tse, Matthew Tv Chan, William Kk Wu

Open access · bronzeAbstract readReview
In one paragraph

Review in Cell proliferation, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers.

0numbers the graph read from it
0cells of the map it votes in
65citing papers in PubMed
4.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

65 citing papers in PubMed, 99 citations in OpenAlex.

  1. Review
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  9. Functional Bidirectionality of ERV-Derived Long Non-Coding RNAs in Humans.International journal of molecular sciences · 2024
    Review
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  20. Review

5 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Xin YuDepartment of Dermatology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Heyi ZhengDepartment of Dermatology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.ORCID http://orcid.org/0000-0002-6557-8861
Gary TseDepartment of Medicine and Therapeutics, The Chinese University of Hong Kong, Sha Tin, Hong Kong.
Matthew Tv ChanDepartment of Anaesthesia and Intensive Care, The Chinese University of Hong Kong, Sha Tin, Hong Kong.
William Kk WuDepartment of Anaesthesia and Intensive Care, The Chinese University of Hong Kong, Sha Tin, Hong Kong.
Chinese University of Hong Kong · HKChinese Academy of Medical Sciences & Peking Union Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Melanoma is the most lethal cutaneous cancer with a highly aggressive and metastatic phenotype. While recent genetic and epigenetic studies have shed new insights into the mechanism of melanoma development, the involvement of regulatory non-coding RNAs remain unclear. Long non-coding RNAs (lncRNAs) are a group of endogenous non-protein-coding RNAs with the capacity to regulate gene expression at multiple levels. Recent evidences have shown that lncRNAs can regulate many cellular processes, such as cell proliferation, differentiation, migration and invasion. In the melanoma, deregulation of a number of lncRNAs, such as HOTAIR, MALAT1, BANCR, ANRIL, SPRY-IT1 and SAMMSON, have been reported. Our review summarizes the functional role of lncRNAs in melanoma and their potential clinical application for diagnosis, prognostication and treatment.

Indexed as

Gene Expression Regulation, NeoplasticHumansMelanomaRNA, Long NoncodingSkin NeoplasmsBANCR long non-coding RNA, humanCDKN2B antisense RNA, humanHOTAIR long untranslated RNA, humanlong non-coding RNA SLNCR1, humanMALAT1 long non-coding RNA, humanRNA, Long NoncodinglncRNAprognosisSLNCR1UCA1

Identifiers

PMID29582492
PMCPMC6528844
OpenAlexW2794835809

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.