ArticleJournal of veterinary internal medicine2018
Evaluation of updated sepsis scoring systems and systemic inflammatory response syndrome criteria and their association with sepsis in equine neonates.
Article in Journal of veterinary internal medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 1 of them a synthesis that pooled it.
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Who cites it
40 citing papers in PubMed, 1 synthesis or guideline pooled it, 83 citations in OpenAlex.
- Clinical predictive models in equine medicine: A systematic review.Equine veterinary journal · 2023Pooled it
- Biomarkers of brain injury in foals with neonatal maladjustment syndrome.Journal of veterinary internal medicine · 2026Article
- [Retrospective evaluation of equine blood cultures sampled between 2022 and 2024].Tierarztliche Praxis. Ausgabe G, Grosstiere/Nutztiere · 2026Article
- Vasopressin stimulation testing in hospitalized foals.Journal of veterinary internal medicine · 2026Article
- Evaluation of oxidative stress in ill neonatal foals: a preliminary study.Journal of veterinary internal medicine · 2026Article
- Retrospective study of blood culture isolates, antimicrobial sensitivity, and survival factors from 243 neonatal foals in Normandy (France).Journal of veterinary internal medicine · 2026Article
- New Diagnostic Score for Sepsis in Adult Horses with Acute Gastrointestinal Disease.Animals : an open access journal from MDPI · 2026Article
- Sequential measurement of serum amyloid A concentrations in ill hospitalized neonatal foals.Journal of veterinary internal medicine · 2026Article
- Evaluation of a subcutaneous continuous glucose monitoring system in critically ill neonatal foals.Journal of veterinary internal medicine · 2026Article
- Bacterial cell-free DNA profiling reveals the co-elevation of multiple bacteria in newborn foals with suspected sepsis.iScience · 2025Article
- The predictive ability of blood-based biomarkers to detect bacteremia in hospitalized neonatal foals.Veterinary journal (London, England : 1997) · 2025Article
- Role of Endoplasmic Reticulum Stress-Associated Genes in Septic Neonatal Foals.Antioxidants (Basel, Switzerland) · 2025Article
- An Overview of Donkey Neonatology.Animals : an open access journal from MDPI · 2025Review
- TLR4 and prostaglandin pathways at the crossroads of endotoxemia-induced lipolysis.Frontiers in immunology · 2025Article
- Clinicopathologic Parameters of Peritoneal Fluid as Predictors of Gastrointestinal Lesions, Complications, and Outcomes in Equine Colic Patients: A Retrospective Study.Animals : an open access journal from MDPI · 2024Article
- Investigation of Extracted Plasma Cell-Free DNA as a Biomarker in Foals with Sepsis.Veterinary sciences · 2024Article
- Equine Placentitis in Mares Induces the Secretion of Pro-Inflammatory CytokineVeterinary sciences · 2023Article
- Article
- The hypothalamic-pituitary-adrenal axis response to ovine corticotropin-releasing-hormone stimulation tests in healthy and hospitalized foals.Journal of veterinary internal medicine · 2023Article
- Serum amyloid A as a marker to detect sepsis and predict outcome in hospitalized neonatal foals.Journal of veterinary internal medicine · 2022Article
Corrections and comments
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Authors and funding
10 authors at 8 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe original equine sepsis score provided a method of identifying foals with sepsis. New variables associated with sepsis have been evaluated, but the sepsis score has not been updated.
objectivesTo evaluate the sensitivity and specificity of 2 updated sepsis scores and the systemic inflammatory response syndrome (SIRS) criteria in regard to detecting sepsis in foals. ANIMALS: Two-hundred and seventy-three ill foals and 25 healthy control foals.
methodsHistorical, physical examination, and clinicopathologic findings were used to calculate the original sepsis score and 2 updated sepsis scores. SIRS criteria were also evaluated. Sepsis scores and positive SIRS scores were statistically compared to foals with sepsis.
resultsOne-hundred and twenty-six foals were septic and 147 sick-nonseptic. The original and updated sepsis scores were significantly higher in septic foals as compared to sick-nonseptic and healthy foals. The sensitivity and specificity of the updated sepsis scores to predict sepsis were not significantly better than those of the original sepsis score. One-hundred and twenty-seven of 273 (46.5%) foals met the original SIRS criteria and 88/273 (32%) foals met the equine neonatal SIRS criteria. The original SIRS criteria had similar sensitivity and specificity for predicting sepsis as did the 3 sepsis scores in our study. CONCLUSIONS AND CLINICAL IMPORTANCE: The updated sepsis scores did not provide improved ability in predicting sepsis. Fulfilling the original SIRS criteria provided similar sensitivity and specificity in predicting sepsis as the modified sepsis score and might serve as a diagnostic aid in identifying foals at risk for sepsis.
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