Evidence map›Paper›PMID 29582338›Full record

ArticleInternational urology and nephrology2018

Health-related quality of life in end-stage renal disease patients: the effects of starting dialysis in the first year after the transition period.

Natascha J H Broers, Remy J H Martens, Bernard Canaud, Tom Cornelis, Tom Dejagere, Nanda M P Diederen, Marc M H Hermans, Constantijn J A M Konings, Frank Stifft, Joris J J M Wirtz and 3 more

Open access · hybridAbstract read
In one paragraph

Article in International urology and nephrology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 39 citations in OpenAlex.

  1. Article
  2. Haemodiafiltration versus high-flux haemodialysis-a Consensus Statement from the EuDial Working Group of the ERA.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 8 institutions in 4 countries.

Natascha J H BroersDivision of Nephrology, Department of Internal Medicine, Maastricht University Medical Center+, PO Box 5800, 6202 AZ, Maastricht, The Netherlands. natascha.broers@mumc.nl.
Remy J H MartensDivision of Nephrology, Department of Internal Medicine, Maastricht University Medical Center+, PO Box 5800, 6202 AZ, Maastricht, The Netherlands.
Bernard CanaudFresenius Medical Care GmbH, Bad Homburg, Germany.
Tom CornelisDepartment of Nephrology, Jessa Hospital, Hasselt, Belgium.
Tom DejagereDepartment of Nephrology, Jessa Hospital, Hasselt, Belgium.
Nanda M P DiederenDivision of Nephrology, Department of Internal Medicine, Maastricht University Medical Center+, PO Box 5800, 6202 AZ, Maastricht, The Netherlands.
Marc M H HermansDepartment of Internal Medicine, Division of Nephrology, Viecuri Medical Center, Venlo, The Netherlands.
Constantijn J A M KoningsDepartment of Internal Medicine, Division of Nephrology, Catharina Hospital Eindhoven, Eindhoven, The Netherlands.
Frank StifftDepartment of Internal Medicine, Division of Nephrology, Zuyderland Medical Center, Sittard-Geleen, The Netherlands.
Joris J J M WirtzDepartment of Internal Medicine, Division of Nephrology, Laurentius Hospital Roermond, Roermond, The Netherlands.
Karel M L LeunissenDivision of Nephrology, Department of Internal Medicine, Maastricht University Medical Center+, PO Box 5800, 6202 AZ, Maastricht, The Netherlands.
Frank M van der SandeDivision of Nephrology, Department of Internal Medicine, Maastricht University Medical Center+, PO Box 5800, 6202 AZ, Maastricht, The Netherlands.
Jeroen P KoomanDivision of Nephrology, Department of Internal Medicine, Maastricht University Medical Center+, PO Box 5800, 6202 AZ, Maastricht, The Netherlands.
Maastricht University · NLJessa Hospital · BECatharina Ziekenhuis · NLFresenius Medical Care (Germany) · DELaurentius Ziekenhuis · NLUniversity Medical Center · USVieCuri Medisch Centrum · NLZuyderland Medisch Centrum · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimsPrevalent dialysis patients have low scores of health-related quality of life (HRQOL) which are associated with increased risk of hospitalization and mortality. Also in CKD-5 non-dialysis patients, HRQOL scores seem to be lower as compared with the general population. This study firstly aimed to compare HRQOL between CKD-5 non-dialysis and prevalent dialysis patients in a cross-sectional analysis and to assess longitudinal changes over 1 year after the dialysis initiation. Secondly, the correlation between HRQOL and physical activity (PA) was explored.

methodsCross-sectional 44 CKD-5 non-dialysis, 29 prevalent dialysis, and 20 healthy controls were included. HRQOL was measured by Short Form-36 questionnaires to measure physical and mental domains of health expressed by the physical component summary (PCS) and mental component summary (MCS) scores. PA was measured by a SenseWear™ pro3. Longitudinally, HRQOL was assessed in 38 CKD-5 non-dialysis patients (who were also part of the cross-sectional analysis), before dialysis initiation until 1 year after dialysis initiation.

resultsPCS scores were significantly lower both in CKD-5 non-dialysis patients and in prevalent dialysis patients as compared with healthy controls (p < 0.001). MCS scores were significantly lower in both CKD-5 non-dialysis patients (p = 0.003), and in dialysis patients (p = 0.022), as compared with healthy controls. HRQOL scores did not change significantly from the CKD-5 non-dialysis phase into the first year after dialysis initiation. PA was significantly related to PCS in both CKD-5 non-dialysis patients (r = 0.580; p < 0.001), and dialysis patients (r = 0.476; p = 0.009).

conclusionsHRQOL is already low in the CKD-5 non-dialysis phase. In the first year after dialysis initiation, HRQOL did not change significantly. Given the correlation between PCS score and PA, physical activity programs may be potential tools to improve HRQOL in both CKD-5 non-dialysis as well as in prevalent dialysis patients.

Indexed as

Quality of LifeRenal DialysisWalkingAdultAgedCross-Sectional StudiesFemaleHumansKidney Failure, ChronicLongitudinal StudiesMaleMiddle AgedSurveys and QuestionnairesDialysisEnd-stage renal diseaseHealth-related quality of lifePhysical Activity

Identifiers

PMID29582338
PMCPMC5986848
OpenAlexW2792639805

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.