Evidence map›Paper›PMID 29582162›Full record

ArticleEuropean journal of nutrition2019

Low adherence to the western and high adherence to the mediterranean dietary patterns could prevent colorectal cancer.

Adela Castelló, Pilar Amiano, Nerea Fernández de Larrea, Vicente Martín, Maria Henar Alonso, Gemma Castaño-Vinyals, Beatriz Pérez-Gómez, Rocío Olmedo-Requena, Marcela Guevara, Guillermo Fernandez-Tardon and 15 more

Registry-linked trialOpen access · greenAbstract read
PubMed Publisher
In one paragraph

Article in European journal of nutrition, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05732623 (Diet obEsity sMoking Epigenetics geneTics biomaRkers Physical Activity), which is not on this map. Cited by 61 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
61citing papers in PubMed, 1 pooled it
23.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05732623 recruitingnot on this mapstarted 2022, after this paper: background citation

Diet obEsity sMoking Epigenetics geneTics biomaRkers Physical Activity: An International Multicenter Case-control Study on Endogenous and Exogenous Risk Factors in Early-onset Colorectal Cancer

Typeobservational_patient_registrySponsorSan Raffaele UniversityRan2022 to 2035Enrolled2,300ConditionsColorectal Cancer, Early Onset Colorectal Cancer, Diet Habit, Risk ReductionArmsSemi Quantitative Food Frequency Questionnaire (SQFFQ)
3 · Its place in the literature

Who cites it

61 citing papers in PubMed, 1 synthesis or guideline pooled it, 165 citations in OpenAlex.

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1 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors at 15 institutions in 1 country.

Adela CastellóCancer Epidemiology Unit, National Center for Epidemiology, Carlos III Institute of Health, Avenida Monforte de Lemos 5, 28029, Madrid, Spain. acastello@isciii.es.ORCID http://orcid.org/0000-0002-1308-9927
Pilar AmianoConsortium for Biomedical Research in Epidemiology and Public Health (CIBERESP), Carlos III Institute of Health, Avenida Monforte de Lemos 5, 28029, Madrid, Spain.
Nerea Fernández de LarreaCancer Epidemiology Unit, National Center for Epidemiology, Carlos III Institute of Health, Avenida Monforte de Lemos 5, 28029, Madrid, Spain.
Vicente MartínThe Research Group in Gene-Environment and Health Interactions, Vegazana Campus, University of León, Campus Vegazana, s/n, 24071, León, Spain.
Maria Henar AlonsoUnit of Biomarkers and Susceptibility, Cancer Prevention and Control Program, Catalan Institute of Oncology (ICO) and IDIBELL, Gran Via km 2.7, 08907, L'Hospitalet de Llobregat, Spain.
Gemma Castaño-VinyalsConsortium for Biomedical Research in Epidemiology and Public Health (CIBERESP), Carlos III Institute of Health, Avenida Monforte de Lemos 5, 28029, Madrid, Spain.
Beatriz Pérez-GómezCancer Epidemiology Unit, National Center for Epidemiology, Carlos III Institute of Health, Avenida Monforte de Lemos 5, 28029, Madrid, Spain.
Rocío Olmedo-RequenaConsortium for Biomedical Research in Epidemiology and Public Health (CIBERESP), Carlos III Institute of Health, Avenida Monforte de Lemos 5, 28029, Madrid, Spain.
Marcela GuevaraConsortium for Biomedical Research in Epidemiology and Public Health (CIBERESP), Carlos III Institute of Health, Avenida Monforte de Lemos 5, 28029, Madrid, Spain.
Guillermo Fernandez-TardonConsortium for Biomedical Research in Epidemiology and Public Health (CIBERESP), Carlos III Institute of Health, Avenida Monforte de Lemos 5, 28029, Madrid, Spain.
Trinidad Dierssen-SotosUniversidad de Cantabria, IDIVAL, Avenida Cardenal Herrera Oria s/n, 39011, Santander, Spain.
Cristobal Llorens-IvorraCentro de Salud Pública de Dénia, Consellería de Sanidad Universal y Salud Pública, Plaza Jaime I, 5, 03700, Denia, Spain.
Jose María HuertaConsortium for Biomedical Research in Epidemiology and Public Health (CIBERESP), Carlos III Institute of Health, Avenida Monforte de Lemos 5, 28029, Madrid, Spain.
Rocío CapeloCentro de Investigación en Salud y Medio Ambiente (CYSMA), Universidad de Huelva, Campus Universitario de El Carmen, 21071, Huelva, Spain.
Tania Fernández-VillaThe Research Group in Gene-Environment and Health Interactions, Vegazana Campus, University of León, Campus Vegazana, s/n, 24071, León, Spain.
Anna Díez-VillanuevaUnit of Biomarkers and Susceptibility, Cancer Prevention and Control Program, Catalan Institute of Oncology (ICO) and IDIBELL, Gran Via km 2.7, 08907, L'Hospitalet de Llobregat, Spain.
Carmen UrtiagaBiodonostia Research Institute, Paseo Dr Beguiristain s/n, 20014, San Sebastián, Spain.
Jesús CastillaConsortium for Biomedical Research in Epidemiology and Public Health (CIBERESP), Carlos III Institute of Health, Avenida Monforte de Lemos 5, 28029, Madrid, Spain.
Jose Juan Jiménez-MoleónConsortium for Biomedical Research in Epidemiology and Public Health (CIBERESP), Carlos III Institute of Health, Avenida Monforte de Lemos 5, 28029, Madrid, Spain.
Víctor MorenoUnit of Biomarkers and Susceptibility, Cancer Prevention and Control Program, Catalan Institute of Oncology (ICO) and IDIBELL, Gran Via km 2.7, 08907, L'Hospitalet de Llobregat, Spain.
Verónica Dávila-BatistaThe Research Group in Gene-Environment and Health Interactions, Vegazana Campus, University of León, Campus Vegazana, s/n, 24071, León, Spain.
Manolis KogevinasConsortium for Biomedical Research in Epidemiology and Public Health (CIBERESP), Carlos III Institute of Health, Avenida Monforte de Lemos 5, 28029, Madrid, Spain.
Nuria AragonésCancer Epidemiology Unit, National Center for Epidemiology, Carlos III Institute of Health, Avenida Monforte de Lemos 5, 28029, Madrid, Spain.
Marina PollánCancer Epidemiology Unit, National Center for Epidemiology, Carlos III Institute of Health, Avenida Monforte de Lemos 5, 28029, Madrid, Spain.
MCC-Spain researchers
Universidad de Granada · ESInstituto de Salud Carlos III · ESBellvitge University Hospital · ESInstitut d'Investigació Biomédica de Bellvitge · ESUniversidad de Alcalá · ESUniversidad de Cantabria · ESUniversitat Pompeu Fabra · ESBasque Government · ESBiogipuzkoa Health Research Institute · ESCentro de Investigación Biomédica en Red de Epidemiología y Salud Pública · ESConselleria de Sanitat Universal i Salut Pública · ESInstituto Murciano de Investigación Biosanitaria · ESUniversidad de Huelva · ESUniversidad de Oviedo · ESUniversitat de Barcelona · ES

Funding

Acción Transversal del Cancer, approved by the Spanish Ministry Council on October 11, 2007; Red Temática de Investigación del Cáncer del ISCIII RD12/0036/0036Carlos III Institute of Health grants PI08/0533Carlos III Institute of Health grants PI08/1359Carlos III Institute of Health grants PI08/1770Carlos III Institute of Health grants PI09/00773Carlos III Institute of Health grants PI09/01286Carlos III Institute of Health grants PI09/01662Carlos III Institute of Health grants PI09/01903Carlos III Institute of Health grants PI09/02078Carlos III Institute of Health grants PI11/00226Carlos III Institute of Health grants PI11/01403Carlos III Institute of Health grants PI11/01810Carlos III Institute of Health grants PI11/01889Carlos III Institute of Health grants PI11/02213Carlos III Institute of Health grants PI12/00265Carlos III Institute of Health grants PI12/00488Carlos III Institute of Health grants PI12/00715Carlos III Institute of Health grants PI12/01270Catalan Government DURSIgrant 2014SGR647Consejería de Salud de la Junta de Andalucía 2009-S0143Consejería de Salud de la Junta de Andalucía PI-0306-2011Consejería de Salud de la Junta de Andalucía PI-0571-2009Conselleria de Sanitat de la Generalitat Valenciana AP_061/10European Commission grants FOOD-CT-2006-036224-HIWATEFundación Marqués de Valdecilla API 10/09Instituto de Salud Carlos III, co-funded by FEDER funds PI14-00613Junta de Castilla y León LE22A10-2Recercaixa 2010ACUP 00310Spanish Ministry of Economy and Competitiveness IJCI-2014-20900
6 · The paper itself

Abstract

purposeTo assess if the associations found between three previously identified dietary patterns with breast, prostate and gastric cancer are also observed for colorectal cancer (CRC).

methodsMCC-Spain is a multicase-control study that collected information of 1629 incident cases of CRC and 3509 population-based controls from 11 Spanish provinces. Western, Prudent and Mediterranean data-driven dietary patterns-derived in another Spanish case-control study-were reconstructed in MCC-Spain. Their association with CRC was assessed using mixed multivariable logistic regression models considering a possible interaction with sex. Risk by tumor site (proximal colon, distal colon, and rectum) was evaluated using multinomial regression models.

resultsWhile no effect of the Prudent pattern on CRC risk was observed, a high adherence to the Western dietary pattern was associated with increased CRC risk for both males [OR

conclusionOur results are consistent with most of the associations previously found between these patterns and breast, prostate and gastric cancer risk and indicate that consuming whole fruits, vegetables, legumes, olive oil, nuts, and fish and avoiding red and processed meat, refined grains, sweets, caloric drinks, juices, convenience food, and sauces might reduce CRC risk.

Indexed as

AdultAgedAged, 80 and overCase-Control StudiesColorectal NeoplasmsDiet, MediterraneanDiet, WesternFemaleHumansMaleMiddle AgedRisk FactorsSpainYoung AdultColonic neoplasmsDietDietary patternsDiet, MediterraneanDiet, WesternPrevention and controlPrincipal component analysisRectal neoplasms

Identifiers

PMID29582162
OpenAlexW2795778468

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.