Evidence map›Paper›PMID 29582120›Full record

ReviewAnalytical and bioanalytical chemistry2018

Consumer-friendly food allergen detection: moving towards smartphone-based immunoassays.

Georgina M S Ross, Monique G E G Bremer, Michel W F Nielen

Abstract readReview
In one paragraph

Review in Analytical and bioanalytical chemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Georgina M S RossRIKILT, Wageningen University and Research, P.O Box 230, 6700 AE, Wageningen, The Netherlands. georgina.ross@wur.nl.
Monique G E G BremerRIKILT, Wageningen University and Research, P.O Box 230, 6700 AE, Wageningen, The Netherlands.
Michel W F NielenRIKILT, Wageningen University and Research, P.O Box 230, 6700 AE, Wageningen, The Netherlands.

Funding

European Union's Horizon 2020 research and innovation programme under the Marie-Sklodowska-Curie grant agreement No 720325, FoodSmartphone
6 · The paper itself

Abstract

In this critical review, we provide a comprehensive overview of immunochemical food allergen assays and detectors in the context of their user-friendliness, through their connection to smartphones. Smartphone-based analysis is centered around citizen science, putting analysis into the hands of the consumer. Food allergies represent a significant worldwide health concern and consumers should be able to analyze their foods, whenever and wherever they are, for allergen presence. Owing to the need for a scientific background, traditional laboratory-based detection methods are generally unsuitable for the consumer. Therefore, it is important to develop simple, safe, and rapid assays that can be linked with smartphones as detectors to improve user accessibility. Smartphones make excellent detection systems because of their cameras, embedded flash functions, portability, connectivity, and affordability. Therefore, this review has summarized traditional laboratory-based methods for food allergen detection such as enzyme-linked-immunosorbent assay, flow cytometry, and surface plasmon resonance, and the potential to modernize these methods by interfacing them with a smartphone readout system, based on the aforementioned smartphone characteristics. This is the first review focusing on smartphone-based food-allergen detection methods designed with the intention of being consumer-friendly. Graphical abstract A smartphone-based food allergen detection system in three easy steps (1) sample preparation, (2) allergen detection on a smartphone using antibodies, which then transmits the data wirelessly, (3) analytical results sent straight to smartphone.

Indexed as

SmartphoneAllergensAnimalsAntibodies, ImmobilizedBiosensing TechniquesElectrochemical TechniquesEquipment DesignFlow CytometryFood HypersensitivityHazard Analysis and Critical Control PointsHumansImmunoassaySurface Plasmon ResonanceAllergensAntibodies, ImmobilizedCitizen scienceConsumerFood allergenImmunoassayMultiplexSmartphone

Identifiers

PMID29582120
PMCPMC6096701

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.