Evidence map›Paper›PMID 29582008›Full record

ArticleJournal of patient experience2018

Patient-Centered Obstetric Care in the Age of Cell-Free Fetal DNA Prenatal Screening.

Patricia K Agatisa, Mary Beth Mercer, Ariane Mitchum, Marissa B Coleridge, Ruth M Farrell

Abstract read
In one paragraph

Article in Journal of patient experience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
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  4. Pooled it
  5. Identifying Strategies to Improve Shared Decision Making for Pregnant Patients' Decisions about Prenatal Genetic Screens and Diagnostic Tests.Medical decision making : an international journal of the Society for Medical Decision Making · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Patricia K AgatisaDepartment of Bioethics, Cleveland Clinic, Cleveland, OH, USA.
Mary Beth MercerOffice of Patient Experience, Cleveland Clinic Center for Personalized Genetic Healthcare, Cleveland, OH, USA.
Ariane MitchumDepartment of Bioethics, Cleveland Clinic, Cleveland, OH, USA.
Marissa B ColeridgeGenomic Medicine Institute, Obstetrics, Gynecology and Women's Health Institute, Cleveland, OH, USA.
Ruth M FarrellDepartment of Bioethics, Cleveland Clinic, Cleveland, OH, USA.

Funding

Preparing for Emerging Applications of Noninvasive Prenatal TestingR21HG008511 · NHGRI · CLEVELAND CLINIC LERNER COM-CWRU · PI FARRELL, RUTH · 2015 to 2016
$436k
NHGRI NIH HHS R21 HG008511
6 · The paper itself

Abstract

purposeThe clinical introduction of innovative prenatal genetic technologies challenges patients and providers to find new ways of fostering informed decision-making in a setting characterized by complexity and uncertainty. As prenatal genetic technology advances, important questions remain about how to structure patient-centered conversations that effectively prepare pregnant patients to make informed choices about the different genetic conditions for which this new form screening may be used.

methodsFocus groups were conducted with 23 pregnant women to identify informational needs and decision-making preferences regarding emerging and anticipated applications of cell-free fetal DNA screening, the newest form of prenatal genetic screening.

resultsParticipants were in favor of obtaining more genetic information about the fetus than provided by conventional screens but acknowledged the challenges inherent in navigating the unique complexities of the decision-making process. The provider-patient relationship was seen as an important resource to navigate the associated uncertainties at each stage of the screening process. Participants emphasized the need for initiatives to support a personalized, accurate, and unbiased discussion about prenatal genetic risk and assessment.

conclusionContinued advances in prenatal genetic screening call for new approaches to structure patient-centered communication to facilitate increasingly complex decisions about fetal genetic risk and assessment.

Indexed as

cell-free fetal DNA screeninginformed decision-makingobstetric carepatient experiencepatient–provider communication

Identifiers

PMID29582008
PMCPMC5862378

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.