Evidence map›Paper›PMID 29581858›Full record

ArticleOncotarget2018

Depleting ovarian cancer stem cells with calcitriol.

Amit Kumar Srivastava, Asim Rizvi, Tiantian Cui, Chunhua Han, Ananya Banerjee, Imrana Naseem, Yanfang Zheng, Altaf A Wani, Qi-En Wang

Open access · diamondAbstract read
In one paragraph

Article in Oncotarget, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 3 pooled it
0.8field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 3 syntheses or guidelines pooled it, 29 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Review
  5. Article
  6. Article
  7. Article
  8. Advances in ovarian tumor stem cells and therapy.Cell biochemistry and biophysics · 2024
    Review
  9. Review
  10. Review
  11. Targeting ovarian cancer stem cells: a new way out.Stem cell research & therapy · 2023
    Review
  12. Review
  13. Review
  14. Review
  15. Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 3 countries.

Amit Kumar Srivastava *Department of Radiology, College of Medicine, The Ohio State University, Columbus, OH 43210, USA.
Asim Rizvi *Department of Radiology, College of Medicine, The Ohio State University, Columbus, OH 43210, USA.
Tiantian CuiDepartment of Radiology, College of Medicine, The Ohio State University, Columbus, OH 43210, USA.
Chunhua HanDepartment of Radiology, College of Medicine, The Ohio State University, Columbus, OH 43210, USA.
Ananya BanerjeeDepartment of Radiology, College of Medicine, The Ohio State University, Columbus, OH 43210, USA.
Imrana NaseemDepartment of Biochemistry, Faculty of Life Sciences, The Aligarh Muslim University, Aligarh, Uttar Pradesh, 202002, India.
Yanfang ZhengOncology Center, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong, 510282, China.
Altaf A WaniDepartment of Radiology, College of Medicine, The Ohio State University, Columbus, OH 43210, USA.
Qi-En WangDepartment of Radiology, College of Medicine, The Ohio State University, Columbus, OH 43210, USA.
The Ohio State University · USAligarh Muslim University · INKIIT University · INZhujiang Hospital · CN

Funding

Translational Therapeutics Research Program (TT)P30CA016058 · NCI · OHIO STATE UNIVERSITY · PI Jennifer A. Woyach · 1985 to 2026
$132.3M
Averting recurrent and resistant ovarian tumorsR01CA211175 · NCI · OHIO STATE UNIVERSITY · PI WANG, QIEN · 2017 to 2021
$2.3M
Role of DDB2 in chemotherapeutic agents-induced apoptosis and platinum resistanceR01CA151248 · NCI · OHIO STATE UNIVERSITY · PI WANG, QIEN · 2011 to 2014
$990k
NCI NIH HHS P30 CA016058NCI NIH HHS R01 CA151248NCI NIH HHS R01 CA211175
6 · The paper itself

Abstract

Cancer stem cells (CSCs) represent the root of many solid tumors including ovarian cancer. Eradication of CSCs represents a novel cancer therapeutic strategy. Calcitriol, also known as 1,25-dihydroxyvitamin D

Indexed as

calcitriolcancer stem cells (CSCs)ovarian cancervitamin D receptor (VDR)Wnt pathway

Identifiers

PMID29581858
PMCPMC5865684
OpenAlexW2790732926

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.