ArticleOncotarget2018
Hypertension predicts a poor prognosis in patients with esophageal squamous cell carcinoma.
Article in Oncotarget, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed, 10 citations in OpenAlex.
- The Potential Role ofMicroorganisms · 2025Review
- Influence of metabolic syndrome on prognosis of patients with surgically treated esophageal cancer: a meta-analysis.Diabetology & metabolic syndrome · 2024Review
- Analysis of the influencing factors in the long-term survival of esophageal cancer.Frontiers in oncology · 2023Article
- Prognostic value of hypertension in patients with nasopharyngeal carcinoma treated with intensity-modulated radiation therapy.Annals of translational medicine · 2021Article
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Authors and funding
10 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWe investigated the relationship between the preoperative hypertension and prognosis of esophageal squamous cell cancer (ESCC) patients who had underwent esophagectomy.
resultsWe detected 52% patients with hypertension, including 317 patients with newly diagnosed hypertension and 194 patients with history of hypertension. Compared with patients of normal blood pressure, all patients with hypertension and newly diagnosed hypertension were observed to have worse overall and ESCC-specific survival outcome (
conclusionsHypertension was an independent risk factor and resulted in inferior prognosis for ESCC patients who had underwent esophagectomy.
methodsA total of 982 ESCC patients who had underwent esophagectomy from August 2010 to December 2015 were enrolled in our study with a follow up of 6 years. The Kaplan-Meier method and log-rank test were respectively used to calculate and compare survival rate, and Cox proportional hazards regression model was applied to identify independent prognostic factors.
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