Evidence map›Paper›PMID 29581780›Full record

ArticleJournal of Cancer2018

Switch of the ovarian cancer cell to a calcifying phenotype in the calcification of ovarian cancer.

Jirui Wen, Zhiwei Zhao, Liwei Huang, Liang Li, Jiman Li, Ye Zeng, Jiang Wu, Yali Miao

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of Cancer, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Jirui WenDepartment of Obstetrics and Gynecology, Key Laboratory of Birth Defects and Related Diseases of Women and Children of MOE, West China Second University Hospital, Sichuan University, Chengdu, P.R. China.
Zhiwei ZhaoWest China School of Basic Medical Sciences & Forensic Medicine, Sichuan University, Chengdu, China.
Liwei HuangWest China School of Stomatology Medicine, Sichuan University, Chengdu, China.
Liang LiWest China School of Basic Medical Sciences & Forensic Medicine, Sichuan University, Chengdu, China.
Jiman LiPathology Department, Sichuan Cancer Hospital, Chengdu, China.
Ye ZengWest China School of Basic Medical Sciences & Forensic Medicine, Sichuan University, Chengdu, China.
Jiang WuWest China School of Basic Medical Sciences & Forensic Medicine, Sichuan University, Chengdu, China.
Yali MiaoDepartment of Obstetrics and Gynecology, Key Laboratory of Birth Defects and Related Diseases of Women and Children of MOE, West China Second University Hospital, Sichuan University, Chengdu, P.R. China.
West China Medical Center of Sichuan University · CNSichuan Cancer Hospital · CNSichuan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe main aim of this study was to study swith of the ovarian cancer cell to a calcifying phenotype in the formation of calcification in ovarian cancer, and to offer some help for ovarian cancer's diagnosis and differentiation therapy.

methodsThe mineralization of ovarian cancer cell lines SKOV3 was induced via calcification medium for 21 d

resultsClassical calcium salt detection methods confirmed that the culture of SKOV3 cells in calcification medium was an appropriate ovarian cancer calcification model

conclusionOur study showed that the switch of the ovarian cancer cell to a calcifying phenotype in the formation of calcification in ovarian cancer. The calcified phenotypic transformation may inform the new prospective in ovarian cancer therapy.

Indexed as

calcificationdifferentiation therapymigrationovarian cancerphenotypic transformation

Identifiers

PMID29581780
PMCPMC5868168
OpenAlexW2792699810

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.