ArticleBMC ear, nose, and throat disorders2018
Treatment, outcomes, and demographics in sinonasal sarcoma: a systematic review of the literature.
Article in BMC ear, nose, and throat disorders, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 32 citations in OpenAlex.
- Comparative validation of current staging systems in sinonasal soft tissue sarcomas: a population-based analysis.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026Article
- Sinonasal Sarcomas Management: An International Consensus Statement.International forum of allergy & rhinology · 2026Article
- Clinical Features and Prognostic Insights in Sinonasal Sarcomas: A 76-Case Single-Institution Experience.Laryngoscope investigative otolaryngology · 2025Article
- Efficacy of toripalimab in combination with anlotinib in recurrent undifferentiated pleomorphic sarcoma of the sinonasal region: a case report with biomarker analysis.Frontiers in immunology · 2025Article
- Angiosarcoma of the Maxillary Sinus: A Case Report.Cureus · 2024Article
- Highly Aggressive Osteosarcoma of the Ethmoids and Maxillary Sinus-A Case of Successful Surgery and Proton Beam Radiotherapy in a 65-Year-Old Man.Medicina (Kaunas, Lithuania) · 2022Article
- Endoscopic endonasal resection of sinonasal teratocarcinosarcoma with intracranial breakthrough: illustrative case.Journal of neurosurgery. Case lessons · 2021Article
- Differences in the Inhibitory Specificity Distinguish the Efficacy of Plant Protease Inhibitors on Mouse Fibrosarcoma.Plants (Basel, Switzerland) · 2021Article
- Head and neck sarcomas: imaging "pearls" and "mimics".The British journal of radiology · 2021Article
- Multimodal Treatment With Orbital Organ Preservation in Adult Patients With Locally Advanced Small-Round-Cell Malignancy of the Nasal Cavity and Paranasal Sinus.Frontiers in oncology · 2021Article
- Malignant peripheral nerve sheath tumor of nasal cavity and paranasal sinus with 13 years of follow-up-A case report and review of literature.Clinical case reports · 2019Article
- Equine sinonasal anaplastic sarcoma infected with multi-drug resistantThe Canadian veterinary journal = La revue veterinaire canadienne · 2019Article
- Incidence and real-world burden of brain metastases from solid tumors and hematologic malignancies in Ontario: a population-based study.Neuro-oncology advancesArticle
- Clinical course and vascular endothelial growth factor signaling system expression in maxillary angiosarcoma: A case report.Science progressArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSarcomas comprise a diverse group of soft tissue mesenchymal malignancies. The sinuses and nasal region are a relatively rare site of sarcomas.
methodsRetrospective review of the literature on sinonasal sarcomas from 1987-2017. Data were analyzed for demographics, treatment type, stage, and histopathologic type. Kaplan-Meier analysis was used to assess and compare survival.
resultsA total of 198 cases of sinonasal sarcoma were identified and analyzed. The median age at diagnosis was 39 years. Overall 5-, 10-, and 20-year survival was 61.3%, 58.9%, and 49.1%, respectively, and disease-free 5-, 10-, and 20-year survival was 53.2%, 49.1%, and 38.3%, respectively. Lymph node metastasis was present at diagnosis in 3.0% of cases, and distant metastasis was present in 3.5% of cases. On univariate analysis T stage, overall stage, treatment type, histopathologic subtype, and presence of distant metastasis significantly affected survival. On multivariate analysis overall stage alone significantly predicted overall survival. Open vs. endoscopic surgery, total radiation dose, and presence of neck metastasis did not significantly affect survival. Combined modality treatment was associated with higher survival rates than single modality therapy.
conclusionsSinonasal sarcoma is a relatively rare malignancy. Lower T and overall stage, lack of distant metastasis, and multimodality therapy were associated with improved survival. Certain histopathologic subtypes were associated with poorer survival.
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