SynthesisJournal of human hypertension2018
Body mass index, abdominal fatness, and hypertension incidence: a dose-response meta-analysis of prospective studies.
Synthesis in Journal of human hypertension, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed, 2 syntheses or guidelines pooled it, 46 citations in OpenAlex.
- Association of body mass index trajectory and hypertension risk: A systematic review of cohort studies and network meta-analysis of 89,094 participants.Frontiers in cardiovascular medicine · 2022Pooled it
- Pooled it
- Screening, Diagnosis, Evaluation, and Staging of Obesity in Adults: Standards of Care in Overweight and Obesity-2026.BMJ open diabetes research & care · 2026Review
- Article
- Impact of Preeclampsia Duration on Long-Term Cardiovascular Disease Risk.Hypertension (Dallas, Tex. : 1979) · 2026Article
- Cardiorespiratory fitness of healthy Polish men and women with various somatotypes.BMC cardiovascular disorders · 2025Article
- CYP2C19 Loss-of-Function Is an Independent Risk Factor of Coronary Artery Disease in Patients With Hypertension.Journal of clinical laboratory analysis · 2025Article
- Body mass index and mortality after elective open abdominal aortic aneurysm repair in a fifteen year multicenter cohort study.Scientific reports · 2025Article
- Relation between obesity and health disorders as revealed by the J-ORBIT clinical information collection system directly linked to electronic medical records (J-ORBIT 1).Journal of diabetes investigation · 2025Article
- Sex differences in the relationship between body mass index in Chinese adolescents and future risk of hypertension: a decade-long cohort study.BMC pediatrics · 2025Article
- Association Between Abdominal Obesity, Body Mass Index, and Hypertension in India: Evidence From a Large Nationally Representative Data.Journal of clinical hypertension (Greenwich, Conn.) · 2025Article
- Patterns of general and abdominal obesity and their association with hypertension control in the iranian hypertensive population: insights from a nationwide study.BMC public health · 2025Article
- Effect of high normal body mass index and its trajectory on risk of new-onset hypertension among Chinese adults: a national prospective cohort study.Frontiers in cardiovascular medicine · 2025Article
- Association of body composition with ambulatory blood pressure among Chinese youths.BMC pediatrics · 2024Article
- The association between body mass index and abdominal obesity with hypertension among South Asian population: findings from nationally representative surveys.Clinical hypertension · 2024Article
- Additive interactions between obesity and insulin resistance on hypertension in a Chinese rural population.BMC public health · 2023Article
- Association between lean body mass and hypertension: A cross-sectional study of 50 159 NHANES participants.Journal of clinical hypertension (Greenwich, Conn.) · 2023Article
- Predicting hypertension by obesity- and lipid-related indices in mid-aged and elderly Chinese: a nationwide cohort study from the China Health and Retirement Longitudinal Study.BMC cardiovascular disorders · 2023Article
- Article
- Association between Arterial Hypertension and Laboratory Markers, Body Composition, Obstructive Sleep Apnea and Autonomic Parameters in Obese Patients.Arquivos brasileiros de cardiologia · 2023Article
Corrections and comments
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Authors and funding
14 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Despite the established relationship of obesity to hypertension, the question as to whether there is a linear association between these two morbidities is unanswered. To quantitatively evaluate the relationship between obesity and hypertension, we carried out a dose-response meta-analysis of studies that looked at the relationship of different adiposity measures to hypertension. We searched PubMed, Embase, and Web of Science databases for articles published before 27 June 2017. A random-effects model was used to pool relative risks and 95% confidence intervals. Restricted cubic spline analysis was used to model the relationship. A total of 59 studies were included. Fifty-seven cohort studies with 125,071 incident cases among 830,685 participants were included in the analysis of body mass index and hypertension with the summary relative risk for per 5-unit increment in body mass index of 1.50 (95% confidence interval: 1.40-1.59). We found that the risk of hypertension in the body mass index analysis was greater in populations where the baseline body mass index was <25 kg/m
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.