Evidence map›Paper›PMID 29581482›Full record

ArticleScientific reports2018

Higher High-Sensitivity C Reactive Protein is Associated with Future Premature Ventricular Contraction: a Community Based Prospective Cohort Study.

Yue Chen, Shouling Wu, Wenyu Li, Binhao Wang, Xu Han, Yiheng Yang, Xumin Guan, Haixu Yu, Bin Waleed Khalid, Huihua Li and 1 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
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  7. Review
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  9. Arrhythmia-Induced Cardiomyopathy: JACC State-of-the-Art Review.Journal of the American College of Cardiology · 2019
    Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Yue ChenDepartment of cardiology, First Affiliated Hospital of Dalian Medical University, Dalian, 116011, China.
Shouling WuDepartment of cardiology, Kailuan Hospital, Hebei United University, Tangshan, China.
Wenyu LiDepartment of cardiology, First Affiliated Hospital of Dalian Medical University, Dalian, 116011, China.
Binhao WangDepartment of cardiology, First Affiliated Hospital of Dalian Medical University, Dalian, 116011, China.ORCID 0000-0001-5341-3878
Xu HanDepartment of cardiology, First Affiliated Hospital of Dalian Medical University, Dalian, 116011, China.
Yiheng YangDepartment of cardiology, First Affiliated Hospital of Dalian Medical University, Dalian, 116011, China.
Xumin GuanDepartment of cardiology, First Affiliated Hospital of Dalian Medical University, Dalian, 116011, China.
Haixu YuDepartment of cardiology, First Affiliated Hospital of Dalian Medical University, Dalian, 116011, China.
Bin Waleed KhalidDepartment of cardiology, First Affiliated Hospital of Dalian Medical University, Dalian, 116011, China.
Huihua LiDepartment of cardiology, First Affiliated Hospital of Dalian Medical University, Dalian, 116011, China. hhli1935@aliyun.com.
Yunlong XiaDepartment of cardiology, First Affiliated Hospital of Dalian Medical University, Dalian, 116011, China. yunlong_xia@126.com.
Dalian Medical University · CNNorth China University of Science and Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We aimed to determine whether hs-CRP is a predictor of future premature ventricular contraction (PVC) events in a community based population. A total of 101,510 participants were recruited at baseline (2006-2007). The follow-up visits were conducted every two years. Participants who were free from PVC at baseline and achieved the fourth visit, or diagnosed of PVC during the subsequent visits were included for analyses. Diagnosis of PVC was based on standard supine resting, 10-s 12-lead ECG. Cox regression was applied to evaluate the association between quartiles of hs-CRP and the incidence of PVCs. 60710 participants (male: 79.9%, mean age 49.4 years) were included for analyses. During a mean follow-up of 74.9 ± 7.4 months, 908 (1.5%) participants were diagnosed with PVC. Participants of the highest quartile of hs-CRP had significantly increased risk of PVC events as compared with the lowest quartile (HR 1.36; 95% CI 1.12-1.66); and stratified analyses showed similar result in males (HR 1.45; 95% CI 1.16-1.80), but not in females (HR 1.12; 95% CI 0.71-1.79). Moreover, elevated serum hs-CRP was associated with future PVC in participants without history of myocardial infarction or stroke (HR 1.34; 95% CI 1.09-1.65). Elevated hs-CRP was an independent predictor of PVC in Chinese population, especially in men.

Indexed as

AdultAgedAnalysis of VarianceChinaChi-Square DistributionC-Reactive ProteinFemaleFollow-Up StudiesHeart VentriclesHumansIncidenceInflammationMaleMiddle AgedProportional Hazards ModelsProspective StudiesC-Reactive Protein

Identifiers

PMID29581482
PMCPMC5979945
OpenAlexW2795243227

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.