Evidence map›Paper›PMID 29581408›Full record

ArticleJournal of bacteriology2018

The Opp (AmiACDEF) Oligopeptide Transporter Mediates Resistance of Serotype 2 Streptococcus pneumoniae D39 to Killing by Chemokine CXCL10 and Other Antimicrobial Peptides.

Kevin E Bruce, Britta E Rued, Ho-Ching Tiffany Tsui, Malcolm E Winkler

Open access · bronzeAbstract read
In one paragraph

Article in Journal of bacteriology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Serine protease HtrA promotesScience advances · 2026
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  6. The five homologous CiaR-controlled Ccn sRNAs ofbioRxiv : the preprint server for biology · 2024
    Article
  7. ImmunobioticInternational journal of molecular sciences · 2023
    Article
  8. Mechanistic insights into the regulation of cell wall hydrolysis by FtsEX and EnvC at the bacterial division site.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  9. Article
  10. Article
  11. Contribution of Puma to Inflammatory Resolution During Early Pneumococcal Pneumonia.Frontiers in cellular and infection microbiology · 2022
    Article
  12. Review
  13. An in vivo atlas of host-pathogen transcriptomes duringProceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  14. Article
  15. Article
  16. Review
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Kevin E BruceDepartment of Biology, Indiana University Bloomington (IUB), Bloomington, Indiana, USA.
Britta E RuedDepartment of Biology, Indiana University Bloomington (IUB), Bloomington, Indiana, USA.
Ho-Ching Tiffany TsuiDepartment of Biology, Indiana University Bloomington (IUB), Bloomington, Indiana, USA tttsui@indiana.edu winklerm@indiana.edu.
Malcolm E WinklerDepartment of Biology, Indiana University Bloomington (IUB), Bloomington, Indiana, USA tttsui@indiana.edu winklerm@indiana.edu.
Indiana University Bloomington · US

Funding

Mechanisms of Chemokine Killing and Resistance of Streptococcus pneumoniaeR01GM114315 · NIGMS · TRUSTEES OF INDIANA UNIVERSITY · PI WINKLER, MALCOLM E. · 2015 to 2018
$1.1M
Graduate Program in Quantitative and Chemical Biology at Indiana University BloomT32GM109825 · NIGMS · TRUSTEES OF INDIANA UNIVERSITY · PI GIEDROC, DAVID P. · 2014 to 2018
$926k
NIGMS NIH HHS R01 GM114315NIGMS NIH HHS T32 GM109825
6 · The paper itself

Abstract

Antimicrobial peptides (AMPs), including chemokines, are produced during infections to kill pathogenic bacteria. To fill in gaps in knowledge about the sensitivities of

Indexed as

AnimalsAnti-Infective AgentsBacterial ProteinsChemokine CXCL10HumansMembrane Transport ProteinsMutationOligopeptidesPneumococcal InfectionsSerogroupSheepStreptococcus pneumoniaeAnti-Infective AgentsBacterial ProteinsChemokine CXCL10Membrane Transport Proteinsoligopeptide permease, BacteriaOligopeptideschemokine antimicrobial activitychemokine resistance mechanismsCXCL10 family chemokinesFtsEX functionsLL-37nisin

Identifiers

PMID29581408
PMCPMC5952386
OpenAlexW2794820295

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.