Evidence map›Paper›PMID 29581312›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2018

Salvatore Rizza, Simone Cardaci, Costanza Montagna, Giuseppina Di Giacomo, Daniela De Zio, Matteo Bordi, Emiliano Maiani, Silvia Campello, Antonella Borreca, Annibale A Puca and 3 more

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 107 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
107citing papers in PubMed, 1 pooled it
8.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

107 citing papers in PubMed, 1 synthesis or guideline pooled it, 189 citations in OpenAlex.

  1. Guideline
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. GSNOR deletion differentially alters age-related cardiac function in a sex-dependent manner.American journal of physiology. Heart and circulatory physiology · 2026
    Article
  12. Targeting the Dynamics Between TAMs and CAR-T Cells in Solid Tumor Therapies.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
  13. Review
  14. Article
  15. Dysregulated ProteinCirculation research · 2025
    Article
  16. Review
  17. Profiling the landscape of cysteine posttranslational modifications in brain aging and neurodegeneration.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2025
    Review
  18. Thermogenic Adipose ADH5 Counteracts Age-related Metabolic Decline.bioRxiv : the preprint server for biology · 2025
    Article
  19. Article
  20. Article

47 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 9 institutions in 3 countries.

Salvatore RizzaDanish Cancer Society Research Center, Center for Autophagy, Recycling and Disease, 2100 Copenhagen, Denmark.
Simone CardaciDivision of Genetics and Cell Biology, Institute for Research and Health Care San Raffaele (IRCCS) Scientific Institute, 20132 Milan, Italy.
Costanza MontagnaDanish Cancer Society Research Center, Center for Autophagy, Recycling and Disease, 2100 Copenhagen, Denmark.
Giuseppina Di GiacomoDepartment of Biology, Tor Vergata University, 00133 Rome, Italy.
Daniela De ZioDanish Cancer Society Research Center, Center for Autophagy, Recycling and Disease, 2100 Copenhagen, Denmark.
Matteo BordiDepartment of Biology, Tor Vergata University, 00133 Rome, Italy.
Emiliano MaianiDanish Cancer Society Research Center, Center for Autophagy, Recycling and Disease, 2100 Copenhagen, Denmark.
Silvia CampelloDepartment of Biology, Tor Vergata University, 00133 Rome, Italy.
Antonella BorrecaInstitute of Cellular Biology and Neuroscience, National Research Council, 00143 Rome, Italy.
Annibale A PucaCardiovascular Research Unit, IRCCS Multimedica, 20138 Milan, Italy.
Jonathan S StamlerInstitute for Transformative Molecular Medicine, Case Western Reserve University, Cleveland, OH 44106.
Francesco CecconiDanish Cancer Society Research Center, Center for Autophagy, Recycling and Disease, 2100 Copenhagen, Denmark.
Giuseppe FilomeniDanish Cancer Society Research Center, Center for Autophagy, Recycling and Disease, 2100 Copenhagen, Denmark; giufil@cancer.dk.
Danish Cancer Society · DKUniversity of Rome Tor Vergata · ITBispebjerg Hospital · DKFondazione Santa Lucia · ITInstitute of Cell Biology and Neurobiology · ITIstituti di Ricovero e Cura a Carattere Scientifico · ITMultiMedica · ITUniversity Hospitals Case Medical Center · USVita-Salute San Raffaele University · IT

Funding

Regulation of Beta-Adrenergic Receptor Signaling by S-NitrosylationP01HL075443 · NHLBI · DUKE UNIVERSITY · PI STAMLER, JONATHAN S. · 2004 to 2019
$26.1M
Project 3 - Personalized cystic fibrosis treatment strategies with synergistic therapies Identified in vitro.P01HL128192 · NHLBI · INDIANA UNIVERSITY INDIANAPOLIS · PI GASTON, BENJAMIN · 2016 to 2020
$12.2M
Restoration and Function of S-Nitrosothiol in Stored BloodR01HL126900 · NHLBI · CASE WESTERN RESERVE UNIVERSITY · PI JONATHAN S. STAMLER · 2016 to 2026
$5.0M
Identification of Novel DenitrosylasesR01GM099921 · NIGMS · CASE WESTERN RESERVE UNIVERSITY · PI STAMLER, JONATHAN S. · 2013 to 2016
$1.4M
NHLBI NIH HHS P01 HL075443NHLBI NIH HHS P01 HL128192NHLBI NIH HHS R01 HL126900NIGMS NIH HHS R01 GM099921
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Mitochondrial DynamicsMitophagyAgingAldehyde OxidoreductasesAnimalsCellular SenescenceHumansMammalsMiceMice, Inbred C57BLMitochondriaNitric OxideNitrosative StressProtein Processing, Post-TranslationalS-NitrosothiolsAldehyde Oxidoreductasesformaldehyde dehydrogenase, glutathione-independentNitric OxideS-NitrosothiolsagingGSNORmitochondriamitophagyS-nitrosylation

Identifiers

PMID29581312
PMCPMC5899480
OpenAlexW2791478032

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.