Evidence map›Paper›PMID 29581305›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2018

Everolimus rescues multiple cellular defects in laminopathy-patient fibroblasts.

Amanda J DuBose, Stephen T Lichtenstein, Noreen M Petrash, Michael R Erdos, Leslie B Gordon, Francis S Collins

Erratum issuedOpen access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 40 papers.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 54 citations in OpenAlex.

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  20. Autophagy in striated muscle diseases.Frontiers in cardiovascular medicine · 2022
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Amanda J DuBoseGenome Technology Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892.
Stephen T LichtensteinGenome Technology Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892.
Noreen M PetrashGenome Technology Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892.
Michael R ErdosGenome Technology Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892.
Leslie B GordonDepartment of Pediatrics, Hasbro Children's Hospital and Warren Alpert Medical School of Brown University, Providence, RI 02903.
Francis S CollinsGenome Technology Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892; collinsf@mail.nih.gov.
National Human Genome Research Institute · USBoston Children's Hospital · USNational Institutes of Health · US

Funding

Hutchinson-Gilford Progeria syndrome--a model for the genetics of aging.ZIAHG200305 · NHGRI · NATIONAL HUMAN GENOME RESEARCH INSTITUTE · PI ERDOS, MICHAEL · 2009 to 2025
$18.1M
Hutchinson-Gilford Progeria Syndrom--Genetic Aging ModelZ01HG200305 · NHGRI · NATIONAL HUMAN GENOME RESEARCH INSTITUTE · PI COLLINS, FRANCIS S. · 2003 to 2008
$2.6M
Intramural NIH HHS Z01 HG200305
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

BiomarkersCell DivisionCell LineCell NucleusCellular SenescenceEverolimusFibroblastsHumansLamin Type AMuscular Dystrophy, Emery-DreifussMutationPhosphorylationProgeriaProtein Processing, Post-TranslationalRibosomal Protein S6TOR Serine-Threonine KinasesBiomarkersEverolimusLamin Type ALMNA protein, humanMTOR protein, humanRibosomal Protein S6TOR Serine-Threonine KinaseseverolimuslaminlaminopathiesmTORprogeria

Identifiers

PMID29581305
PMCPMC5910873
OpenAlexW2792025169

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.