ArticleProceedings of the National Academy of Sciences of the United States of America2018
Small proline-rich protein 2B drives stress-dependent p53 degradation and fibroblast proliferation in heart failure.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
26 citing papers in PubMed, 38 citations in OpenAlex.
- Crosstalk between ubiquitination and other post-translational modifications in cardiovascular diseases.iScience · 2026Review
- SPRR2B knockdown inhibits the proliferation and inflammatory response in M5-treated human HaCaT keratinocytes.European journal of histochemistry : EJH · 2026Article
- SportsXbiodata: A web platform for integrative analysis of exercise-induced gene and protein expression.iScience · 2026Article
- Cardiac Fibroblasts Enhance MMP2 Activity to Suppress Gap Junction Function in Cardiomyocytes.Applied biochemistry and biotechnology · 2024Article
- Circulating microRNA-409-5p and USP7 are associated with left ventricular remodeling in patients with acute myocardial infarction.BMC cardiovascular disorders · 2024Article
- Deletion of ASPP1 in myofibroblasts alleviates myocardial fibrosis by reducing p53 degradation.Nature communications · 2024Article
- p53 Regulates the Extent of Fibroblast Proliferation and Fibrosis in Left Ventricle Pressure Overload.Circulation research · 2023Article
- SIRT3 Deficiency Enhances Ferroptosis and Promotes Cardiac Fibrosis via p53 Acetylation.Cells · 2023Article
- p53 and Myofibroblast Apoptosis in Organ Fibrosis.International journal of molecular sciences · 2023Review
- SIRT6 Mitigates Heart Failure With Preserved Ejection Fraction in Diabetes.Circulation research · 2022Article
- Changes to Urinary Proteome in High-Fat-DietBiomolecules · 2022Article
- Transcriptional regulation of cardiac fibroblast phenotypic plasticity.Current opinion in physiology · 2022Article
- Altered Regulation of mRNA and miRNA Expression in Epithelial and Stromal Tissue of Keratoconus Corneas.Investigative ophthalmology & visual science · 2022Article
- Neonatal Scn1b-null mice have sinoatrial node dysfunction, altered atrial structure, and atrial fibrillation.JCI insight · 2022Article
- Cardiac fibroblasts secrete exosome microRNA to suppress cardiomyocyte pyroptosis in myocardial ischemia/reperfusion injury.Molecular and cellular biochemistry · 2022Article
- Hippo signaling in cardiac fibroblasts during development, tissue repair, and fibrosis.Current topics in developmental biology · 2022Review
- Prevention of Fibrosis and Pathological Cardiac Remodeling by Salinomycin.Circulation research · 2021Article
- The regulatory roles of p53 in cardiovascular health and disease.Cellular and molecular life sciences : CMLS · 2021Review
- Fibroblast contributions to ischemic cardiac remodeling.Cellular signalling · 2021Review
- Small Proline-Rich Protein 2B Facilitates Gastric Adenocarcinoma Proliferation via MDM2-p53/p21 Signaling Pathway.OncoTargets and therapy · 2021Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
Abstract
Heart disease is associated with the accumulation of resident cardiac fibroblasts (CFs) that secrete extracellular matrix (ECM), leading to the development of pathological fibrosis and heart failure. However, the mechanisms underlying resident CF proliferation remain poorly defined. Here, we report that small proline-rich protein 2b (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.