Evidence map›Paper›PMID 29581236›Full record

ArticleThe Journal of biological chemistry2018

Cryo-EM structure of

Anoop Narayanan, Frank S Vago, Kunpeng Li, M Zuhaib Qayyum, Dinesh Yernool, Wen Jiang, Katsuhiko S Murakami

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

53 citing papers in PubMed, 79 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Anoop NarayananDepartment of Biochemistry and Molecular Biology, The Center for RNA Molecular Biology, The Pennsylvania State University, University Park, Pennsylvania 16802; Department of Biological Sciences, Markey Center for Structural Biology, Purdue University, West Lafayette, Indiana 47906.
Frank S VagoDepartment of Biological Sciences, Markey Center for Structural Biology, Purdue University, West Lafayette, Indiana 47906.
Kunpeng LiDepartment of Biological Sciences, Markey Center for Structural Biology, Purdue University, West Lafayette, Indiana 47906.
M Zuhaib QayyumDepartment of Biochemistry and Molecular Biology, The Center for RNA Molecular Biology, The Pennsylvania State University, University Park, Pennsylvania 16802.
Dinesh YernoolDepartment of Biological Sciences, Markey Center for Structural Biology, Purdue University, West Lafayette, Indiana 47906.
Wen JiangDepartment of Biological Sciences, Markey Center for Structural Biology, Purdue University, West Lafayette, Indiana 47906. Electronic address: jiang12@purdue.edu.
Katsuhiko S MurakamiDepartment of Biochemistry and Molecular Biology, The Center for RNA Molecular Biology, The Pennsylvania State University, University Park, Pennsylvania 16802. Electronic address: kum14@psu.edu.
Purdue University West Lafayette · USPennsylvania State University · US

Funding

X-Ray Crystallographic Studies of Multi-Subunit Nucleic Acid PolymerasesR01GM087350 · NIGMS · PENNSYLVANIA STATE UNIVERSITY, THE · PI MURAKAMI, KATSUHIKO · 2010 to 2018
$2.6M
Structure and Function of Sodium-Calcium ExchangersR01GM093142 · NIGMS · PURDUE UNIVERSITY · PI YERNOOL, DINESH A · 2011 to 2015
$1.4M
NIGMS NIH HHS R01 GM087350NIGMS NIH HHS R01 GM093142
6 · The paper itself

Abstract

First step of gene expression is transcribing the genetic information stored in DNA to RNA by the transcription machinery including RNA polymerase (RNAP). In

Indexed as

Promoter Regions, GeneticCryoelectron MicroscopyDNA, BacterialDNA-Binding ProteinsDNA-Directed RNA PolymerasesEscherichia coliEscherichia coli ProteinsGenes, BacterialGenes, EssentialNucleic Acid ConformationProtein BindingProtein ConformationSigma FactorTranscription, GeneticTranscription Initiation SiteDNA, BacterialDNA-Binding ProteinsDNA-Directed RNA PolymerasesEscherichia coli ProteinsRNA polymerase sigma 70Sigma Factorcryo-electron microscopycryo-EMopen complexpromoterpromoter DNARNA polymerasestructural biologytranscriptionσ non-conserved region

Identifiers

PMID29581236
PMCPMC5949986
OpenAlexW2791783580

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.