Evidence map›Paper›PMID 29581101›Full record

ArticleCMAJ open2018

Catastrophic drug coverage: utilization insights from the Ontario Trillium Drug Program.

Mina Tadrous, Simon Greaves, Diana Martins, Muhammad M Mamdani, David N Juurlink, Tara Gomes

Abstract read
In one paragraph

Article in CMAJ open, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mina TadrousAffiliations: Li Ka Shing Knowledge Institute (Tadrous, Gomes), St. Michael's Hospital; Institute for Clinical Evaluative Sciences (Tadrous, Greaves, Martins, Mamdani, Juurlink, Gomes); Leslie Dan Faculty of Pharmacy (Tadrous, Mamdani, Gomes), University of Toronto; Institute of Health Policy, Management and Evaluation (Mamdani, Juurlink, Gomes), University of Toronto; Li Ka Shing Centre for Healthcare Analytics Research and Training (Mamdani), St. Michael's Hospital; Sunnybrook Research Institute (Juurlink), Toronto, Ont.
Simon GreavesAffiliations: Li Ka Shing Knowledge Institute (Tadrous, Gomes), St. Michael's Hospital; Institute for Clinical Evaluative Sciences (Tadrous, Greaves, Martins, Mamdani, Juurlink, Gomes); Leslie Dan Faculty of Pharmacy (Tadrous, Mamdani, Gomes), University of Toronto; Institute of Health Policy, Management and Evaluation (Mamdani, Juurlink, Gomes), University of Toronto; Li Ka Shing Centre for Healthcare Analytics Research and Training (Mamdani), St. Michael's Hospital; Sunnybrook Research Institute (Juurlink), Toronto, Ont.
Diana MartinsAffiliations: Li Ka Shing Knowledge Institute (Tadrous, Gomes), St. Michael's Hospital; Institute for Clinical Evaluative Sciences (Tadrous, Greaves, Martins, Mamdani, Juurlink, Gomes); Leslie Dan Faculty of Pharmacy (Tadrous, Mamdani, Gomes), University of Toronto; Institute of Health Policy, Management and Evaluation (Mamdani, Juurlink, Gomes), University of Toronto; Li Ka Shing Centre for Healthcare Analytics Research and Training (Mamdani), St. Michael's Hospital; Sunnybrook Research Institute (Juurlink), Toronto, Ont.
Muhammad M MamdaniAffiliations: Li Ka Shing Knowledge Institute (Tadrous, Gomes), St. Michael's Hospital; Institute for Clinical Evaluative Sciences (Tadrous, Greaves, Martins, Mamdani, Juurlink, Gomes); Leslie Dan Faculty of Pharmacy (Tadrous, Mamdani, Gomes), University of Toronto; Institute of Health Policy, Management and Evaluation (Mamdani, Juurlink, Gomes), University of Toronto; Li Ka Shing Centre for Healthcare Analytics Research and Training (Mamdani), St. Michael's Hospital; Sunnybrook Research Institute (Juurlink), Toronto, Ont.
David N JuurlinkAffiliations: Li Ka Shing Knowledge Institute (Tadrous, Gomes), St. Michael's Hospital; Institute for Clinical Evaluative Sciences (Tadrous, Greaves, Martins, Mamdani, Juurlink, Gomes); Leslie Dan Faculty of Pharmacy (Tadrous, Mamdani, Gomes), University of Toronto; Institute of Health Policy, Management and Evaluation (Mamdani, Juurlink, Gomes), University of Toronto; Li Ka Shing Centre for Healthcare Analytics Research and Training (Mamdani), St. Michael's Hospital; Sunnybrook Research Institute (Juurlink), Toronto, Ont.
Tara GomesAffiliations: Li Ka Shing Knowledge Institute (Tadrous, Gomes), St. Michael's Hospital; Institute for Clinical Evaluative Sciences (Tadrous, Greaves, Martins, Mamdani, Juurlink, Gomes); Leslie Dan Faculty of Pharmacy (Tadrous, Mamdani, Gomes), University of Toronto; Institute of Health Policy, Management and Evaluation (Mamdani, Juurlink, Gomes), University of Toronto; Li Ka Shing Centre for Healthcare Analytics Research and Training (Mamdani), St. Michael's Hospital; Sunnybrook Research Institute (Juurlink), Toronto, Ont.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCatastrophic drug coverage programs help those with high drug-costs to reduce the burden of out-of-pocket expenses. We set out to measure changes in utilization, spending and demographic profiles of people accessing Ontario's catastrophic drug program, the Trillium Drug Program.

methodsWe conducted a cross-sectional time-series analysis examining quarterly utilization and spending trends among medications reimbursed by the Trillium Drug Program in Ontario, Canada from Jan. 1, 2000, to Dec. 31, 2016. In each of 2000, 2005, 2010 and 2015, we described the population of beneficiaries, including demographic information, health care utilization and medication utilization.

resultsOver our study period, use of the Trillium Drug Program increased threefold from 3.6 beneficiaries per 1000 to 10.9 beneficiaries per 1000 Ontarians, and total government spending on the program increased by over 700%, reaching $487 million in 2016. Between 2000 and 2015, there was an increase in the number of beneficiaries who were under the age of 35 years (19.6% to 25.3%;

interpretationIncreasing use of Ontario's catastrophic drug program highlights the growing burden of high drug prices for Canadians. With a growing number of expensive drugs being approved in Canada, we anticipate that spending and use of the catastrophic drug program will continue to expand.

Identifiers

PMID29581101
PMCPMC5878951

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.