Evidence map›Paper›PMID 29581096›Full record

ArticleThe EMBO journal2018

p110α of PI3K is necessary and sufficient for quiescence exit in adult muscle satellite cells.

Gang Wang, Han Zhu, Chenghao Situ, Lifang Han, Youqian Yu, Tom H Cheung, Kai Liu, Zhenguo Wu

Open access · bronzeAbstract read
In one paragraph

Article in The EMBO journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 42 citations in OpenAlex.

  1. A Myocyte-Enriched Long Non-Coding RNA NRMLncR Enhances Myogenesis in Mouse.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026
    Article
  2. bioRxiv : the preprint server for biology · 2026
    Article
  3. MgScience advances · 2025
    Article
  4. Overexpression of CPT1A disrupts the maintenance and regenerative function of muscle stem cells.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2024
    Article
  5. Article
  6. Article
  7. FOXO transcription factors as mediators of stress adaptation.Nature reviews. Molecular cell biology · 2024
    Review
  8. Article
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  10. Article
  11. Review
  12. Review
  13. Article
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  15. Review
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  17. Article
  18. Actions and interactions of IGF-I and MMPs during muscle regeneration.Seminars in cell & developmental biology · 2021
    Review
  19. Paxbp1 controls a key checkpoint for cell growth and survival during early activation of quiescent muscle satellite cells.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Gang WangDivision of Life Science, Center for Stem Cell Research, Center for Systems Biology and Human Health, the State Key Laboratory in Neuroscience, Hong Kong University of Science & Technology, Kowloon Hong Kong, China.
Han ZhuDivision of Life Science, Center for Stem Cell Research, Center for Systems Biology and Human Health, the State Key Laboratory in Neuroscience, Hong Kong University of Science & Technology, Kowloon Hong Kong, China.
Chenghao SituDivision of Life Science, Center for Stem Cell Research, Center for Systems Biology and Human Health, the State Key Laboratory in Neuroscience, Hong Kong University of Science & Technology, Kowloon Hong Kong, China.
Lifang HanDivision of Life Science, Center for Stem Cell Research, Center for Systems Biology and Human Health, the State Key Laboratory in Neuroscience, Hong Kong University of Science & Technology, Kowloon Hong Kong, China.
Youqian YuDivision of Life Science, Center for Stem Cell Research, Center for Systems Biology and Human Health, the State Key Laboratory in Neuroscience, Hong Kong University of Science & Technology, Kowloon Hong Kong, China.
Tom H CheungDivision of Life Science, Center for Stem Cell Research, Center for Systems Biology and Human Health, the State Key Laboratory in Neuroscience, Hong Kong University of Science & Technology, Kowloon Hong Kong, China.
Kai LiuDivision of Life Science, Center for Stem Cell Research, Center for Systems Biology and Human Health, the State Key Laboratory in Neuroscience, Hong Kong University of Science & Technology, Kowloon Hong Kong, China.
Zhenguo WuDivision of Life Science, Center for Stem Cell Research, Center for Systems Biology and Human Health, the State Key Laboratory in Neuroscience, Hong Kong University of Science & Technology, Kowloon Hong Kong, China bczgwu@ust.hk.ORCID 0000-0003-3049-8324
Hong Kong University of Science and Technology · HK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Adult mouse muscle satellite cells (MuSCs) are quiescent in uninjured muscles. Upon injury, MuSCs exit quiescence

Indexed as

AnimalsCell ProliferationCells, CulturedClass I Phosphatidylinositol 3-KinasesMice, Mutant StrainsMuscle, SkeletalRegenerationSatellite Cells, Skeletal Muscle1-phosphatidylinositol 3-kinase p110 subunit, mouseClass I Phosphatidylinositol 3-KinasesFoxOsmTORC1muscle satellite cellsphosphatidylinositol 3‐kinasequiescence exit

Identifiers

PMID29581096
PMCPMC5897777
OpenAlexW2790017422

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.