ArticleThe American journal of cardiology2018
Alcohol Consumption and Risk of Coronary Artery Disease (from the Million Veteran Program).
Article in The American journal of cardiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 4 syntheses or guidelines pooled it, 39 citations in OpenAlex.
- A burden of proof study on alcohol consumption and ischemic heart disease.Nature communications · 2024Pooled it
- Association between Wine Consumption with Cardiovascular Disease and Cardiovascular Mortality: A Systematic Review and Meta-Analysis.Nutrients · 2023Pooled it
- Alcohol Consumption and Cardiovascular Health.The American journal of medicine · 2022Pooled it
- Associations between Low to Moderate Consumption of Alcoholic Beverage Types and Health Outcomes: A Systematic Review.Alcohol and alcoholism (Oxford, Oxfordshire) · 2022Pooled it
- Health effects associated with alcohol consumption: a Burden of Proof study.Nature health · 2026Article
- Alcohol Consumption and Acute Coronary Syndrome: Epidemiology, Pathophysiology, and Clinical Perspectives.Journal of clinical medicine · 2025Review
- Association between alcoholic beverage consumption and cerebral small vessel disease burden.The journal of prevention of Alzheimer's disease · 2025Article
- Alcohol use, heavy episodic drinking, and associated cardiovascular risk in Guyana.Revista panamericana de salud publica = Pan American journal of public health · 2025Article
- Geographical variations and predictors of coronary artery disease mortality in Turkiye: an environmental and behavioral analysis.BMC cardiovascular disorders · 2024Article
- New Modifiable Risk Factors Influencing Coronary Artery Disease Severity.International journal of molecular sciences · 2024Review
- Implications of Physical Activity in Reducing Alcohol Use for Women Veterans: A Narrative Review.Women's health reports (New Rochelle, N.Y.) · 2024Review
- Atrial Fibrillation and Chronic Coronary Ischemia: A Challenging Vicious Circle.Life (Basel, Switzerland) · 2023Review
- Alcohol and Cardiovascular Disease: Helpful or Hurtful.Reviews in cardiovascular medicine · 2023Review
- Association of lipid, inflammatory, and metabolic biomarkers with age at onset for incident cardiovascular disease.BMC medicine · 2022Article
- Is drinking wine in moderation good for health or not?European heart journal supplements : journal of the European Society of Cardiology · 2022Article
- Article
- Alcohol Use Disorders and Their Harmful Effects on the Contractility of Skeletal, Cardiac and Smooth Muscles.Advances in drug and alcohol research · 2021Article
- Racial and Ethnic Disparities in U.S. Veteran Health Characteristics.International journal of environmental research and public health · 2021Article
- Gender Differences in Demographic and Health Characteristics of the Million Veteran Program Cohort.Women's health issues : official publication of the Jacobs Institute of Women's Health · 2019Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 4 institutions in 1 country.
Funding
Abstract
Moderate alcohol consumption has been associated with a lower risk of coronary artery disease (CAD) in the general population but has not been well studied in US veterans. We obtained self-reported alcohol consumption from Million Veteran Program participants. Using electronic health records, CAD events were defined as 1 inpatient or 2 outpatient diagnosis codes for CAD, or 1 code for a coronary procedure. We excluded participants with prevalent CAD (n = 69,995) or incomplete alcohol information (n = 8,449). We used a Cox proportional hazards model to estimate hazard ratios and 95% confidence intervals for CAD, adjusting for age, gender, body mass index, race, smoking, education, and exercise. Among 156,728 participants, the mean age was 65.3 years (standard deviation = 12.1) and 91% were men. There were 6,153 CAD events during a mean follow-up of 2.9 years. Adjusted hazard ratios (95% confidence intervals) for CAD were 1.00 (reference), 1.02 (0.92 to 1.13), 0.83 (0.74 to 0.93), 0.77 (0.67 to 0.87), 0.71 (0.62 to 0.81), 0.62 (0.51 to 0.76), 0.58 (0.46 to 0.74), and 0.95 (0.85 to 1.06) for categories of never drinker; former drinker; current drinkers of ≤0.5 drink/day, >0.5 to 1 drink/day, >1 to 2 drinks/day, >2 to 3 drinks/day, and >3 to 4 drinks/day; and heavy drinkers (>4 drinks/day) or alcohol use disorder, respectively. For a fixed amount of ethanol, intake at ≥3 days/week was associated with lower CAD risk compared with ≤1 day/week. Beverage preference (beer, wine, or liquor) did not influence the alcohol-CAD relation. Our data show a lower risk of CAD with light-to-moderate alcohol consumption among US veterans, and drinking frequency may provide a further reduction in risk.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.