Evidence map›Paper›PMID 29580380›Full record

ArticleeLife2018

Resilience of small intestinal beneficial bacteria to the toxicity of soybean oil fatty acids.

Sara C Di Rienzi, Juliet Jacobson, Elizabeth A Kennedy, Mary E Bell, Qiaojuan Shi, Jillian L Waters, Peter Lawrence, J Thomas Brenna, Robert A Britton, Jens Walter and 1 more

Open access · goldAbstract read
In one paragraph

Article in eLife, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.0field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 3 countries.

Sara C Di RienziDepartment of Microbiome Science, Max Planck Institute for Developmental Biology, Tübingen, Germany.ORCID http://orcid.org/0000-0002-6188-663X
Juliet JacobsonDepartment of Molecular Biology and Genetics, Cornell University, Ithaca, United States.
Elizabeth A KennedyDepartment of Molecular Biology and Genetics, Cornell University, Ithaca, United States.
Mary E BellDepartment of Molecular Biology and Genetics, Cornell University, Ithaca, United States.
Qiaojuan ShiDepartment of Molecular Biology and Genetics, Cornell University, Ithaca, United States.
Jillian L WatersDepartment of Microbiome Science, Max Planck Institute for Developmental Biology, Tübingen, Germany.
Peter LawrenceDivision of Nutritional Sciences, Cornell University, Ithaca, United States.
J Thomas BrennaDivision of Nutritional Sciences, Cornell University, Ithaca, United States.
Robert A BrittonDepartment of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, United States.
Jens WalterDepartment of Agricultural, Food, and Nutritional Science, University of Alberta, Edmonton, Canada.ORCID http://orcid.org/0000-0003-1754-172X
Ruth E LeyDepartment of Microbiome Science, Max Planck Institute for Developmental Biology, Tübingen, Germany.ORCID http://orcid.org/0000-0002-9087-1672
Cornell University · USBaylor College of Medicine · USUniversity of Alberta · CA

Funding

Development of immunization strategies to reshape pathogenic microbiomesDP2OD007444 · OD · CORNELL UNIVERSITY · PI LEY, RUTH EMILY · 2010 to 2010
$2.3M
NIH HHS DP2 OD007444NIH HHS DP2OD007444
6 · The paper itself

Abstract

Over the past century, soybean oil (SBO) consumption in the United States increased dramatically. The main SBO fatty acid, linoleic acid (18:2), inhibits in vitro the growth of lactobacilli, beneficial members of the small intestinal microbiota. Human-associated lactobacilli have declined in prevalence in Western microbiomes, but how dietary changes may have impacted their ecology is unclear. Here, we compared the in vitro and in vivo effects of 18:2 on

Indexed as

AnimalsDrug Resistance, BacterialGastrointestinal MicrobiomeIntestine, SmallLactobacillus johnsoniiLimosilactobacillus reuteriLinoleic AcidMiceMutationSelection, GeneticSoybean OilLinoleic AcidSoybean Oildirected evolutioninfectious diseaselactobacilluslinoleic acidmicrobiologymicrobiomemousesmall intestinesoybean oil

Identifiers

PMID29580380
PMCPMC5902164
OpenAlexW2734554187

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.