Evidence map›Paper›PMID 29580370›Full record

ArticleThe Journal of general virology2018

Identification of a newly described OsHV-1 µvar from the North Adriatic Sea (Italy).

Miriam Abbadi, Gianpiero Zamperin, Michele Gastaldelli, Francesco Pascoli, Umberto Rosani, Adelaide Milani, Alessia Schivo, Emanuele Rossetti, Edoardo Turolla, Lorenzo Gennari and 3 more

Open access · hybridAbstract read
In one paragraph

Article in The Journal of general virology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
4.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 55 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Miriam AbbadiIstituto Zooprofilattico Sperimentale Delle Venezie, Legnaro (PD), Italy.
Gianpiero ZamperinIstituto Zooprofilattico Sperimentale Delle Venezie, Legnaro (PD), Italy.
Michele GastaldelliIstituto Zooprofilattico Sperimentale Delle Venezie, Legnaro (PD), Italy.
Francesco PascoliIstituto Zooprofilattico Sperimentale Delle Venezie, Legnaro (PD), Italy.
Umberto RosaniDepartment of Biology, University of Padova, Padova (PD), Italy.
Adelaide MilaniIstituto Zooprofilattico Sperimentale Delle Venezie, Legnaro (PD), Italy.
Alessia SchivoIstituto Zooprofilattico Sperimentale Delle Venezie, Legnaro (PD), Italy.
Emanuele RossettiConsorzio Cooperative Pescatori del Polesine, Scardovari (RO), Italy.
Edoardo TurollaIstituto Delta Laboratorio CRIM, Goro (FE), Italy.
Lorenzo GennariBivi s.r.l., Civitanova Marche (MC), Italy.
Anna ToffanIstituto Zooprofilattico Sperimentale Delle Venezie, Legnaro (PD), Italy.
Giuseppe ArcangeliIstituto Zooprofilattico Sperimentale Delle Venezie, Legnaro (PD), Italy.
Paola VenierDepartment of Biology, University of Padova, Padova (PD), Italy.
Istituto Zooprofilattico Sperimentale delle Venezie · ITUniversity of Padua · ITL'organizzazione Ospedale di Civitanova M · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The surveillance activities for abnormal bivalve mortality events in Italy include the diagnosis of ostreid herpesvirus type 1 (OsHV-1) in symptomatic oysters. OsHV-1-positive oysters (Crassostrea gigas) were used as a source for in vivo virus propagation and a virus-rich sample was selected to perform shotgun sequencing based on Illumina technology. Starting from this unpurified supernatant sample from gills and mantle, we generated 3.5 million reads (2×300 bp) and de novo assembled the whole genome of an Italian OsHV-1 microvariant (OsHV-1-PT). The OsHV-1-PT genome encodes 125 putative ORFs, 7 of which had not previously been predicted in other sequenced Malacoherpesviridae. Overall, OsHV-1-PT displays typical microvariant OsHV-1 genome features, while few polymorphisms (0.08 %) determine its uniqueness. As little is known about the genetic determinants of OsHV-1 virulence, comparing complete OsHV-1 genomes supports a better understanding of the virus pathogenicity and provides new insights into virus-host interactions.

Indexed as

Genome, ViralAnimalsCrassostreaDNA, ViralDNA VirusesItalyOpen Reading FramesPhylogenyPolymorphism, GeneticDNA, Viralcomplete genomeCrassostrea gigasde novo assemblynext generation sequencingOsHV-1-PTOstreid herpesvirus type 1 μVar

Identifiers

PMID29580370
PMCPMC5994699
OpenAlexW2793417125

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.