Evidence map›Paper›PMID 29580296›Full record

ArticleInfectious diseases of poverty2018

Spatial distribution of leprosy in India: an ecological study.

Kyra H Grantz, Winnie Chabaari, Ramolotja Kagiso Samuel, Buri Gershom, Laura Blum, Lee Worden, Sarah Ackley, Fengchen Liu, Thomas M Lietman, Alison P Galvani and 2 more

Open access · goldAbstract read
In one paragraph

Article in Infectious diseases of poverty, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 23 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 8 institutions in 4 countries.

Kyra H GrantzDepartment of Biology, University of Florida, Gainesville, FL, USA.
Winnie ChabaariDST/NRF Center for Excellence in Epidemiological Modeling and Analysis (SACEMA), Stellenbosch, South Africa.
Ramolotja Kagiso SamuelDST/NRF Center for Excellence in Epidemiological Modeling and Analysis (SACEMA), Stellenbosch, South Africa.
Buri GershomAfrican Institute of Mathematical Sciences, Muizenberg, South Africa.
Laura BlumUniversity of California, Berkeley, CA, USA.
Lee WordenFrancis I. Proctor Foundation for Research in Ophthalmology, University of California, San Francisco, CA, USA.
Sarah AckleyFrancis I. Proctor Foundation for Research in Ophthalmology, University of California, San Francisco, CA, USA.
Fengchen LiuFrancis I. Proctor Foundation for Research in Ophthalmology, University of California, San Francisco, CA, USA.
Thomas M LietmanFrancis I. Proctor Foundation for Research in Ophthalmology, University of California, San Francisco, CA, USA.
Alison P GalvaniYale University, New Haven, CT, USA.
Lalitha PrajnaAravind Eye Hospital, Madurai, Tamil Nadu, India.
Travis C PorcoFrancis I. Proctor Foundation for Research in Ophthalmology, University of California, San Francisco, CA, USA. travis.porco@ucsf.edu.ORCID http://orcid.org/0000-0001-8813-3171
University of California, San Francisco · USStellenbosch University · ZAAfrican Institute for Mathematical Sciences · ZAAravind Eye Hospital · INFoundation University Islamabad · PKUniversity of California, Berkeley · USUniversity of Florida · USYale University · US

Funding

Impacts of Individual and Social Behavior on Influenza Dynamics and ControlU01GM087719 · NIGMS · YALE UNIVERSITY · PI GALVANI, ALISON P, MEYERS, LAUREN ANCEL · 2009 to 2018
$6.3M
Accelerating viral outbreak detection in US cities using mechanistic models, machine learning and diverse geospatial dataR01AI151176 · NIAID · YALE UNIVERSITY · PI GALVANI, ALISON P, MEYERS, LAUREN ANCEL · 2020 to 2024
$3.9M
"Modeling contact investigation and rapid response"U01GM087728 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI PORCO, TRAVIS CHRISTIAN · 2011 to 2015
$2.2M
Evaluating the social influences that impact vaccination decisionsU01GM105627 · NIGMS · YALE UNIVERSITY · PI GALVANI, ALISON P · 2013 to 2017
$1.6M
International Clinics on Infectious Disease Dynamics and Data (ICI3D Program)R25GM102149 · NIGMS · UNIVERSITY OF FLORIDA · PI PULLIAM, JULIET RC, WELTE, ALEX · 2012 to 2015
$696k
National Institutes of Health R25GM102149National Institutes of Health U01-GM087719National Institutes of Health (US) U01-GM087728NIAID NIH HHS R01 AI151176NIGMS NIH HHS R25 GM102149NIGMS NIH HHS U01 GM087719NIGMS NIH HHS U01 GM087728NIGMS NIH HHS U01 GM105627
6 · The paper itself

Abstract

backgroundAs leprosy elimination becomes an increasingly realistic goal, it is essential to determine the factors that contribute to its persistence. We evaluate social and economic factors as predictors of leprosy annual new case detection rates within India, where the majority of leprosy cases occur.

methodsWe used correlation and linear mixed effect regressions to assess whether poverty, illiteracy, nighttime satellite radiance (an index of development), and other covariates can explain district-wise annual new case detection rate and Grade 2 disability diagnoses.

resultsWe find only weak evidence of an association between poverty and annual new case detection rates at the district level, though illiteracy and satellite radiance are statistically significant predictors of leprosy at the district level. We find no evidence of rapid decline over the period 2008-2015 in either new case detection or new Grade 2 disability.

conclusionsOur findings suggest a somewhat higher rate of leprosy detection, on average, in poorer districts; the overall effect is weak. The divide between leprosy case detection and true incidence of clinical leprosy complicates these results, particularly given that the detection rate is likely disproportionately lower in impoverished settings. Additional information is needed to distinguish the determinants of leprosy case detection and transmission during the elimination epoch.

Indexed as

HumansIndiaLeprosySocioeconomic FactorsSpatial AnalysisHansen’s diseaseIndiaLeprosyPovertySpatial

Identifiers

PMID29580296
PMCPMC5870368
OpenAlexW2796140932

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.