Evidence map›Paper›PMID 29580280›Full record

ArticleInfectious diseases of poverty2018

Report of the first international workshop on onchocerciasis-associated epilepsy.

Robert Colebunders, Michel Mandro, Alfred K Njamnshi, Michel Boussinesq, An Hotterbeekx, Joseph Kamgno, Sarah O'Neill, Adrian Hopkins, Patrick Suykerbuyk, Maria-Gloria Basáñez and 6 more

Open access · goldAbstract readEditorial
In one paragraph

Article in Infectious diseases of poverty, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 35 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Macrophage migration inhibitory factor in Nodding syndrome.PLoS neglected tropical diseases · 2021
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Review
  16. High prevalence of epilepsy in an onchocerciasis endemic health zone in the Democratic Republic of the Congo, despite 14 years of community-directed treatment with ivermectin: A mixed-method assessment.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2019
    Article
  17. Review
  18. Nodding syndrome research, lessons learned from the NSETHIO project.Global mental health (Cambridge, England) · 2019
    Review
  19. Article
  20. Onchodermatitis: Where Are We Now?Tropical medicine and infectious disease · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 11 institutions in 8 countries.

Robert ColebundersGlobal Health Institute, University of Antwerp, Antwerp, Belgium. robert.colebunders@uantwerpen.be.ORCID http://orcid.org/0000-0002-1919-1340
Michel MandroProvincial Health Division of Ituri, Bunia, Democratic Republic of the Congo.
Alfred K NjamnshiDepartment of Neurology, Yaoundé Central Hospital/University of Yaoundé 1, Brain Research Africa Initiative (BRAIN), Yaoundé, Cameroon.
Michel BoussinesqInstitut de Recherche pour le Développement (IRD), Montpellier, France.
An HotterbeekxGlobal Health Institute, University of Antwerp, Antwerp, Belgium.
Joseph KamgnoCentre for Research on Filariasis and other Tropical Diseases (CRFilMT), and Faculty of Medicine and Biomedical Sciences, University of Yaoundé 1, Yaoundé, Cameroon.
Sarah O'NeillDepartment of Public Health, Institute of Tropical Medicine, Antwerp, Belgium.
Adrian HopkinsNeglected and Disabling Diseases of Poverty Consultant, Kent, UK.
Patrick SuykerbuykGlobal Health Institute, University of Antwerp, Antwerp, Belgium.
Maria-Gloria BasáñezLondon Centre for Neglected Tropical Disease Research, Imperial College London, London, UK.
Rory J PostLondon School of Hygiene & Tropical Medicine and Liverpool John Moores University, London, UK.
Belén PedriqueDrugs for Neglected Diseases initiative, Geneva, Switzerland.
Pierre-Marie PreuxPreux Pierre-Marie, INSERM, University Limoges, CHU Limoges, UMR_S 1094, Tropical Neuroepidemiology, Institute of Neuroepidemiology and Tropical Neurology, CNRS FR 3503 GEIST, 87000, Limoges, France.
Wilma A StolkDepartment of Public Health, Erasmus MC, University Medical Centre Rotterdam, Rotterdam, The Netherlands.
Thomas B NutmanLaboratory of Parasitic Diseases, National Institutes of Health, Bethesda, Maryland, USA.
Richard IdroMakerere University, College of Health Sciences, Kampala, Uganda.
University of Antwerp · BEUniversité de Yaoundé I · CMAgropolis International · FRCentre National de la Recherche Scientifique · FRDrugs for Neglected Diseases Initiative · CHErasmus MC · NLInstituut voor Tropische Geneeskunde · BELondon Centre for Neglected Tropical Disease Research · GBMakerere University · UGNational Institutes of Health · USUniversity of London · GB

Funding

Clinical And Therapeutic Studies Of Human Filariasis and Related DiseasesZIAAI000439 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI NUTMAN, THOMAS · 2009 to 2025
$14.8M
H2020 European Research Council 671055Medical Research Council MR/M025489/1
6 · The paper itself

Abstract

backgroundRecently, several epidemiological studies performed in Onchocerca volvulus-endemic regions have suggested that onchocerciasis-associated epilepsy (OAE) may constitute an important but neglected public health problem in many countries where onchocerciasis is still endemic. MAIN TEXT: On October 12-14

conclusionsAlthough the exact pathophysiological mechanism underlying OAE remains unknown, there is increasing evidence that by controlling and eliminating onchocerciasis, OAE will also disappear. Therefore, OAE constitutes an additional argument for strengthening onchocerciasis elimination efforts. Given the high numbers of people with epilepsy in O. volvulus-endemic regions, more advocacy is urgently needed to provide anti-epileptic treatment to improve the quality of life of these individuals and their families.

Indexed as

EpilepsyOnchocerciasisAdolescentAfricaBelgiumChildChild, PreschoolCost of IllnessHumansInfectious Disease MedicineNodding SyndromePrevalenceAfricaBurden of diseaseEpilepsyNakalanga syndromeNodding syndromeOnchocerciasisPrevalence

Identifiers

PMID29580280
PMCPMC5868050
OpenAlexW2804085302

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.