ArticleInfectious diseases of poverty2018
Distinct clinical characteristics and helminth co-infections in adult tuberculosis patients from urban compared to rural Tanzania.
Article in Infectious diseases of poverty, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 5 of them syntheses that pooled it.
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Who cites it
20 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- Prevalence of human schistosomiasis in various regions of Tanzania Mainland and Zanzibar: A systematic review and meta-analysis of studies conducted for the past ten years (2013-2023).PLoS neglected tropical diseases · 2024Pooled it
- Intestinal helminth co-infection and associated factors among pulmonary tuberculosis patients in Africa and Asia: a systematic review and meta-analysis.BMC infectious diseases · 2023Pooled it
- A systematic literature review of schistosomiasis in urban and peri-urban settings.PLoS neglected tropical diseases · 2021Pooled it
- Strongyloidiasis in Africa: Systematic Review and Meta-Analysis on Prevalence, Diagnostic Methods, and Study Settings.BioMed research international · 2020Pooled it
- Are intestinal helminths playing a positive role in tuberculosis risk? A systematic review and meta-analysis.PloS one · 2019Pooled it
- Ultrasound in managing extrapulmonary tuberculosis: a randomized controlled two-center study.BMC infectious diseases · 2020Trial
- The human immunome in the post-schistosomiasis mass drug administration era.PLoS neglected tropical diseases · 2026Review
- Helminth Infection, Gut Microbiome Alterations, and Their Impact on Pulmonary Tuberculosis Susceptibility.Journal of tropical medicine · 2026Review
- Incidence and risk factors for tuberculosis at a rural HIV clinic in Uganda, 2012-2019; A retrospective cohort study.BMC public health · 2025Article
- Beyond schistosomiasis: unraveling co-infections and altered immunity.Clinical microbiology reviews · 2024Review
- Strong effect of demographic changes on Tuberculosis susceptibility in South Africa.PLOS global public health · 2024Article
- Strong Effect of Demographic Changes on Tuberculosis Susceptibility in South Africa.medRxiv : the preprint server for health sciences · 2023Article
- Prevalence and Clinical Relevance ofOpen journal of epidemiology · 2023Article
- Seroepidemiology of Strongyloides spp. Infection in Balimo, Western Province, Papua New Guinea.The American journal of tropical medicine and hygiene · 2023Article
- Mantoux test defaulters in rural population attending tertiary care hospital in a tuberculosis endemic area.Journal of family medicine and primary care · 2022Article
- Spatio-temporal variation in tuberculosis incidence and risk factors for the disease in a region of unbalanced socio-economic development.BMC public health · 2021Article
- Facility-based surveillance for influenza and respiratory syncytial virus in rural Zambia.BMC infectious diseases · 2021Article
- The Sputum Microbiome in Pulmonary Tuberculosis and Its Association With Disease Manifestations: A Cross-Sectional Study.Frontiers in microbiology · 2021Article
- Extrapulmonary tuberculosis in HIV-infected patients in rural Tanzania: The prospective Kilombero and Ulanga antiretroviral cohort.PloS one · 2020Article
- Intestinal parasites and HIV in Ethiopian tuberclosis patients: A systematic review and meta-analysis.Current therapeutic research, clinical and experimental · 2020Article
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Abstract
backgroundDifferences in rural and urban settings could account for distinct characteristics in the epidemiology of tuberculosis (TB). We comparatively studied epidemiological features of TB and helminth co-infections in adult patients from rural and urban settings of Tanzania.
methodsAdult patients (≥ 18 years) with microbiologically confirmed pulmonary TB were consecutively enrolled into two cohorts in Dar es Salaam, with ~ 4.4 million inhabitants (urban), and Ifakara in the sparsely populated Kilombero District with ~ 400 000 inhabitants (rural). Clinical data were obtained at recruitment. Stool and urine samples were subjected to diagnose helminthiases using Kato-Katz, Baermann, urine filtration, and circulating cathodic antigen tests. Differences between groups were assessed by χ
resultsBetween August 2015 and February 2017, 668 patients were enrolled, 460 (68.9%) at the urban and 208 (31.1%) at the rural site. Median patient age was 35 years (interquartile range [IQR]: 27-41.5 years), and 454 (68%) were males. Patients from the rural setting were older (median age 37 years vs. 34 years, P = 0.003), had a lower median body mass index (17.5 kg/m
conclusionsClinical characteristics and helminth co-infections pattern differ in TB patients in urban and rural Tanzania. The differences underline the need for setting-specific, tailored public health interventions to improve clinical management of TB and comorbidities.
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