ArticleAsian Pacific journal of cancer prevention : APJCP2018
Alcohol Consumption as a Risk Factor for Breast Cancer Development: A Case-Control Study in Brazil
Article in Asian Pacific journal of cancer prevention : APJCP, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.
- Risk factors for breast cancer in women: an update review.Medical oncology (Northwood, London, England) · 2022Pooled it
- Alcohol consumption and cancer progression: Mechanistic insights, immune dysregulation, and public health implications.Translational oncology · 2026Review
- Recent Advances (2020-2025) in Estrogen and ER-Positive Breast Cancer: Receptor Signaling, Tumor Microenvironment, Endocrine Therapy Resistance and Innovative Treatment Strategies-A Comprehensive Review.Cancer management and research · 2026Review
- Alcohol Consumption and Breast and Ovarian Cancer Development: Molecular Pathways and Mechanisms.Current issues in molecular biology · 2024Review
- Review
- Cancer Risk Factors in Southern Brazil: Report of a Comprehensive, Matched Case-Control Study.JCO global oncology · 2023Article
- Mammary Glands of Women, Female Dogs and Female Rats: Similarities and Differences to Be Considered in Breast Cancer Research.Veterinary sciences · 2023Review
- Alcohol & cancer: Evidence to action.The Indian journal of medical research · 2022Article
- Foods may modify responsiveness to cancer immune checkpoint blockers by altering both the gut microbiota and activation of estrogen receptors in immune cells.Frontiers in microbiomes · 2022Review
- Breast cancer in Trinidad and Tobago: Etiopathogenesis, histopathology and receptor study.Journal of family medicine and primary care · 2021Article
- Thyroid disease is associated with an increased risk of breast cancer: a systematic review and meta-analysis.Gland surgery · 2021Article
- Anti-inflammatory effect from extracts of Red Chinese cabbage and Aronia in LPS-stimulated RAW 264.7 cells.Food science & nutrition · 2020Article
- Alcohol's Effects on Breast Cancer in Women.Alcohol research : current reviews · 2020Review
- Epidemiological characteristics of and risk factors for breast cancer in the world.Breast cancer (Dove Medical Press) · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Alcohol consumption is a well-established risk factor for breast cancer, but the evidence is mostly from developed countries. Brazil is going through a rapid demographic expansion, and studies of this relationship are also needed in such unexplored settings. Methods: We assessed the relationship between alcohol consumption and breast cancer risk among 1,506 Brazilian women (406 cases and 1,100 controls). Regression models were used to calculate odds ratios (OR) and 95% confidence intervals (CI). All statistical tests were two-tailed. Results: The mean age of the 1,506 women was 42.0 (standard deviation, ±15.0) years. There was a significant association between breast cancer and age, body mass index, age at menarche, menstrual flow and menstrual cycle. Multivariate analysis showed an increased risk of invasive breast cancer in regular alcohol consumers (<50 years old: OR 4.7; 95% CI 1.4–16.2; ≥50 years old: OR 3.9; 95% CI 1.2–13.4) compared with abstainers or occasional drinkers. Women with a regular alcohol intake for 10 years or more who were less than 50 years old had a threefold higher risk of developing breast cancer (OR 3.0; 95% CI 1.2–7.6). Conclusion: Regular alcohol consumption increases the risk of breast cancer mainly among women less than 50 years old.
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