Evidence map›Paper›PMID 29579729›Full record

ArticleColloids and surfaces. B, Biointerfaces2018

Antibacterial activity on superhydrophobic titania nanotube arrays.

Kevin Bartlet, Sanli Movafaghi, Lakshmi Prasad Dasi, Arun K Kota, Ketul C Popat

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Colloids and surfaces. B, Biointerfaces, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 92 citations in OpenAlex.

  1. Review
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  10. Nature-Inspired Surface Structures Design for Antimicrobial Applications.International journal of molecular sciences · 2023
    Review
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  20. Potential of Superhydrophobic Surface for Blood-Contacting Medical Devices.International journal of molecular sciences · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Kevin BartletDepartment of Mechanical Engineering, Colorado State University, Campus Delivery 1374, Fort Collins, CO 80523, USA.
Sanli MovafaghiDepartment of Mechanical Engineering, Colorado State University, Campus Delivery 1374, Fort Collins, CO 80523, USA.
Lakshmi Prasad DasiDepartment of Biomedical Engineering, The Ohio State University, Dorothy Davis Heart and Lung Research Institute, Columbus, OH 43210, USA.
Arun K KotaDepartment of Mechanical Engineering, Colorado State University, Campus Delivery 1374, Fort Collins, CO 80523, USA; Department of Chemical Engineering, Colorado State University, Campus Delivery 1370, Fort Collins, CO 80523, USA; School of Biomedical Engineering, Colorado State University, Campus Delivery 1376, Fort Collins, CO 80523, USA.
Ketul C PopatDepartment of Mechanical Engineering, Colorado State University, Campus Delivery 1374, Fort Collins, CO 80523, USA; School of Biomedical Engineering, Colorado State University, Campus Delivery 1376, Fort Collins, CO 80523, USA. Electronic address: ketul.popat@colostate.edu.
Colorado State University · USLung Institute · US

Funding

Superhydrophobic Heart Valve ProsthesisR01HL135505 · NHLBI · OHIO STATE UNIVERSITY · PI DASI, LAKSHMI PRASAD, KOTA, ARUN KUMAR · 2017 to 2020
$2.9M
Superomniphobic flow controlled prosthetic heart valveR21HL139208 · NHLBI · OHIO STATE UNIVERSITY · PI DASI, LAKSHMI PRASAD, KOTA, ARUN KUMAR · 2018 to 2019
$408k
NHLBI NIH HHS R01 HL135505NHLBI NIH HHS R21 HL139208
6 · The paper itself

Abstract

Bacterial infections are a serious issue for many implanted medical devices. Infections occur when bacteria colonize the surface of an implant and form a biofilm, a barrier which protects the bacterial colony from antibiotic treatments. Further, the anti-bacterial treatments must also be tailored to the specific bacteria that is causing the infection. The inherent protection of bacteria in the biofilm, differences in bacteria species (gram-positive vs. gram-negative), and the rise of antibiotic-resistant strains of bacteria makes device-acquired infections difficult to treat. Recent research has focused on reducing biofilm formation on medical devices by modifying implant surfaces. Proposed methods have included antibacterial surface coatings, release of antibacterial drugs from surfaces, and materials which promote the adhesion of non-pathogenic bacteria. However, no approach has proven successful in repelling both gram-positive and gram-negative bacteria. In this study, we have evaluated the ability of superhydrophobic surfaces to reduce bacteria adhesion regardless of whether the bacteria are gram-positive or gram-negative. Although superhydrophobic surfaces did not repel bacteria completely, they had minimal bacteria attached after 24 h and more importantly no biofilm formation was observed.

Indexed as

Anti-Bacterial AgentsBacteriaBacterial AdhesionBiofilmsGram-Negative BacteriaMicrobial Sensitivity TestsNanotubesTitaniumAnti-Bacterial AgentsTitaniumtitanium dioxideAnti-bacterial surfacesBacterial infectionBiofilm formationSuperhydrophobic surfaces

Identifiers

PMID29579729
PMCPMC5911253
OpenAlexW2790063833

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.