Evidence map›Paper›PMID 29579578›Full record

ReviewCurrent opinion in cell biology2018

The molecular machines that traffic signaling receptors into and out of cilia.

Maxence V Nachury

Abstract readReview
In one paragraph

Review in Current opinion in cell biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 111 papers.

0numbers the graph read from it
0cells of the map it votes in
111citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

111 citing papers in PubMed.

  1. Loss of U11/U12 spliceosome geneLife science alliance · 2026
    Article
  2. Review
  3. Primary cilia and neural computation.Journal of biomedical science · 2026
    Review
  4. Stereotypical interciliary contacts in abioRxiv : the preprint server for biology · 2026
    Article
  5. Article
  6. Article
  7. G Protein-Coupled Receptor Signal Intersection at the Primary Cilium.BioEssays : news and reviews in molecular, cellular and developmental biology · 2025
    Review
  8. Article
  9. Review
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Primary cilia and their role in preeclampsia.International journal of medical sciences · 2025
    Review
  19. Review
  20. Article

51 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Maxence V NachuryUCSF School of Medicine, Department of Ophthalmology, United States. Electronic address: maxence.nachury@ucsf.edu.

Funding

Rapid-Prototyping and Design CoreP30EY002162 · NEI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI LAKKARAJU, APARNA · 1985 to 2024
$16.8M
Quality control of the primary cilium proteomeR01GM089933 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Maxence V Nachury · 2010 to 2026
$5.8M
Proteomics of Primary Cilia through Proximity LabelingR21HD087126 · NICHD · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI NACHURY, MAXENCE V · 2016 to 2017
$435k
NEI NIH HHS P30 EY002162NICHD NIH HHS R21 HD087126NIGMS NIH HHS R01 GM089933
6 · The paper itself

Abstract

Cilia are surface-exposed organelles that dynamically concentrate signaling molecules to organize sensory, developmental and homeostatic pathways. Entry and exit of signaling receptors is germane to the processing of signals and the molecular machines for entry and exit have started to emerge. The IFT-A complex and its membrane recruitment factor Tulp3 complex promotes the entry of signaling receptors into cilia while the BBSome and its membrane recruitment factor Arl6

Indexed as

CiliaHumansProtein TransportSignal Transduction

Identifiers

PMID29579578
PMCPMC5949257

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.