ArticleEarly human development2018
Term-equivalent functional brain maturational measures predict neurodevelopmental outcomes in premature infants.
Article in Early human development, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Neurodevelopmental consequences of preterm punctate white matter lesions: a systematic review.Pediatric research · 2023Pooled it
- Multimodal Assessment of Cerebral Perfusion and EEG Maturation in Preterm Infants at Term-Equivalent Age.Children (Basel, Switzerland) · 2026Article
- Serial amplitude-integrated electroencephalography trajectories and brain-injury-associated functional immaturity in extremely preterm infants.Frontiers in pediatrics · 2026Article
- What's that noise-tackling sound pollution in the NICU: a systematic review.Frontiers in pediatrics · 2026Review
- Functional connectivity as a prognostic biomarker for neurodevelopmental outcomes in preterm infants without severe brain injury.Brain communications · 2025Article
- The Predictive Value of Amplitude-Integrated Electroencephalography for the Neurodevelopmental Outcomes of Preterm Newborns at 12 Months Corrected Age.Children (Basel, Switzerland) · 2024Article
- aEEG in the first 3 days after extremely preterm delivery relates to neurodevelopmental outcomes.Journal of perinatology : official journal of the California Perinatal Association · 2024Article
- An Amplitude-Integrated EEG Evaluation of Neonatal Opioid Withdrawal Syndrome.American journal of perinatology · 2024Observational
- A practical approach toward interpretation of amplitude integrated electroencephalography in preterm infants.European journal of pediatrics · 2022Review
- Value of amplitude-integrated electroencephalogram combined with quantitative indices of cranial magnetic resonance imaging in predicting short-term neurodevelopment in moderately and late preterm infants: a prospective study.Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2021Article
- Quantitative Preterm EEG Analysis: The Need for Caution in Using Modern Data Science Techniques.Frontiers in pediatrics · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
backgroundTerm equivalent age (TEA) brain MRI identifies preterm infants at risk for adverse neurodevelopmental outcomes. But some infants may experience neurodevelopmental impairments even in the absence of neuroimaging abnormalities.
objectiveEvaluate the association of TEA amplitude-integrated EEG (aEEG) measures with neurodevelopmental outcomes at 24-36 months corrected age.
methodsWe performed aEEG recordings and brain MRI at TEA (mean post-menstrual age of 39 (±2) weeks in a cohort of 60 preterm infants born at a mean gestational age of 26 (±2) weeks. Forty-four infants underwent Bayley Scales of Infant Development, 3rd Edition (BSID-III) testing at 24-36 months corrected age. Developmental delay was defined by a score greater than one standard deviation below the mean (<85) in any domain. An ROC curve was constructed and a value of SEF
resultsInfants with developmental delay in any domain had significantly lower values of SEF
conclusionsaEEG may be used at TEA as a new tool for risk stratification of infants at higher risk of poor neurodevelopmental outcomes. Therefore, a larger study is needed to validate these results in premature infants at low and high risk of brain injury.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.