Evidence map›Paper›PMID 29579454›Full record

ArticleThe Journal of investigative dermatology2018

A Fibroblast Is Not a Fibroblast Is Not a Fibroblast.

Michael S Hu, Alessandra L Moore, Michael T Longaker

Abstract readComment
In one paragraph

Article in The Journal of investigative dermatology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Review
  8. A fine balance in tendon healing.Nature cell biology · 2019
    Article
  9. Evolving insights into the cellular and molecular pathogenesis of fibrosis in systemic sclerosis.Translational research : the journal of laboratory and clinical medicine · 2019
    Review
  10. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Michael S HuHagey Laboratory for Pediatric Regenerative Medicine, Department of Surgery, Division of Plastic and Reconstructive Surgery, Stanford University School of Medicine, Stanford, California, USA.
Alessandra L MooreHagey Laboratory for Pediatric Regenerative Medicine, Department of Surgery, Division of Plastic and Reconstructive Surgery, Stanford University School of Medicine, Stanford, California, USA.
Michael T LongakerHagey Laboratory for Pediatric Regenerative Medicine, Department of Surgery, Division of Plastic and Reconstructive Surgery, Stanford University School of Medicine, Stanford, California, USA; Institute for Stem Cell Biology and Regenerative Medicine, Stanford University, Stanford, California, USA. Electronic address: longaker@stanford.edu.

Funding

Fibroblast lineage mechanisms of scarless skin healingR01GM116892 · NIGMS · STANFORD UNIVERSITY · PI LONGAKER, MICHAEL T, LORENZ, HERMANN PETER · 2017 to 2020
$1.2M
NIGMS NIH HHS R01 GM116892
6 · The paper itself

Abstract

Fibrosis after injury is a huge public health concern, leading to morbidity, mortality, and expenditure of billions of health care dollars. Recent mouse studies have shown that dermal fibroblasts are heterogeneous. New research using single-cell RNA sequencing to identify major fibroblast populations in humans is paving the way to a better understanding of fibroblast heterogeneity and fibrosis.

Indexed as

Dipeptidyl Peptidase 4FibroblastsAnimalsCalcium-Binding ProteinsCells, CulturedFibrosisHumansMembrane ProteinsMiceMicrofilament ProteinsOxygenasesSecreted Frizzled-Related ProteinsSkinCalcium-Binding Proteinsdimethylaniline monooxygenase (N-oxide forming)Dipeptidyl Peptidase 4DPP4 protein, humanLSP1 protein, humanLsp1 protein, mouseMembrane ProteinsMicrofilament ProteinsOxygenasesSecreted Frizzled-Related ProteinsSFRP2 protein, humanSfrp2 protein, mouse

Identifiers

PMID29579454
PMCPMC6540758

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.