Evidence map›Paper›PMID 29579341›Full record

ArticleBiometrics2018

Bayesian nonparametric generative models for causal inference with missing at random covariates.

Jason Roy, Kirsten J Lum, Bret Zeldow, Jordan D Dworkin, Vincent Lo Re, Michael J Daniels

Abstract read
In one paragraph

Article in Biometrics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Review
  2. Article
  3. Enriched Pitman-Yor processes.Scandinavian journal of statistics, theory and applications · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Bayesian clustering of multiple zero-inflated outcomes.Philosophical transactions. Series A, Mathematical, physical, and engineering sciences · 2023
    Article
  12. Article
  13. Review
  14. Bayesian semi-parametric G-computation for causal inference in a cohort study with MNAR dropout and death.Journal of the Royal Statistical Society. Series C, Applied statistics · 2021
    Article
  15. Article
  16. Discussion of PENCOMP.Journal of the American Statistical Association · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jason RoyDepartment of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania, Philadelphia, Pennsylvania 19104, U.S.A.ORCID 0000-0003-4237-0504
Kirsten J LumDepartment of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania, Philadelphia, Pennsylvania 19104, U.S.A.
Bret ZeldowDepartment of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania, Philadelphia, Pennsylvania 19104, U.S.A.
Jordan D DworkinDepartment of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania, Philadelphia, Pennsylvania 19104, U.S.A.
Vincent Lo ReDepartment of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania, Philadelphia, Pennsylvania 19104, U.S.A.
Michael J DanielsDepartment of Statistics, University of Florida, Gainesville, Florida 32611, U.S.A.

Funding

Alcohol Associated Outcomes Among HIV+/-Aging VeteransU01AA013566 · NIAAA · YALE UNIVERSITY · PI JUSTICE, AMY CAROLINE · 2002 to 2005
$10.1M
Alcohol and Multisubstance Use in the Veterans Aging Cohort StudyU01AA020790 · NIAAA · YALE UNIVERSITY · PI JUSTICE, AMY CAROLINE · 2011 to 2020
$7.7M
Sex Disparities in Overall Response to ART Among HIV Infected IndividualsU24AA020794 · NIAAA · YALE UNIVERSITY · PI JUSTICE, AMY CAROLINE · 2011 to 2020
$5.5M
BAYESIAN APPROACHES FOR MISSINGNESS AND CAUSALITY IN CANCER AND BEHAVIOR STUDIESR01CA183854 · NCI · UNIVERSITY OF TEXAS AT AUSTIN · PI DANIELS, MICHAEL J · 2014 to 2019
$1.7M
Non-Parametric Bayesian Methods for Causal InferenceR01GM112327 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI ROY, JASON A · 2014 to 2017
$1.4M
NCI NIH HHS R01 CA183854NIAAA NIH HHS U01 AA013566NIAAA NIH HHS U01 AA020790NIAAA NIH HHS U24 AA020794NIGMS NIH HHS R01 GM112327
6 · The paper itself

Abstract

We propose a general Bayesian nonparametric (BNP) approach to causal inference in the point treatment setting. The joint distribution of the observed data (outcome, treatment, and confounders) is modeled using an enriched Dirichlet process. The combination of the observed data model and causal assumptions allows us to identify any type of causal effect-differences, ratios, or quantile effects, either marginally or for subpopulations of interest. The proposed BNP model is well-suited for causal inference problems, as it does not require parametric assumptions about the distribution of confounders and naturally leads to a computationally efficient Gibbs sampling algorithm. By flexibly modeling the joint distribution, we are also able to impute (via data augmentation) values for missing covariates within the algorithm under an assumption of ignorable missingness, obviating the need to create separate imputed data sets. This approach for imputing the missing covariates has the additional advantage of guaranteeing congeniality between the imputation model and the analysis model, and because we use a BNP approach, parametric models are avoided for imputation. The performance of the method is assessed using simulation studies. The method is applied to data from a cohort study of human immunodeficiency virus/hepatitis C virus co-infected patients.

Indexed as

Bayes TheoremCausalityComputer SimulationAlgorithmsBiometryCohort StudiesCoinfectionConfounding Factors, EpidemiologicHepatitis CHIV InfectionsHumansModels, StatisticalObservational Studies as TopicBayesian modelingCausal effectClusterEnriched Dirichlet process mixture modelMissing dataObservational studies

Identifiers

PMID29579341
PMCPMC7568223

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.