Evidence map›Paper›PMID 29579263›Full record

ArticleThe Journal of infectious diseases2018

Etiology of Placental Plasmodium falciparum Malaria in African Women.

Michael F Ofori, Helena Lamptey, Emmanuel K Dickson, Eric Kyei-Baafour, Lars Hviid

Open access · hybridAbstract read
In one paragraph

Article in The Journal of infectious diseases, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Serology reveals micro-differences inFrontiers in parasitology · 2023
    Article
  9. Article
  10. A Genotyping Study in Benin Comparing the Carriage of Plasmodium falciparum Infections Before Pregnancy and in Early Pregnancy: Story of a Persistent Infection.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2021
    Article
  11. Article
  12. Article
  13. Placental Malaria.Current tropical medicine reports · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Michael F OforiNoguchi Memorial Institute for Medical Research, University of Ghana, Legon.
Helena LampteyNoguchi Memorial Institute for Medical Research, University of Ghana, Legon.
Emmanuel K DicksonNoguchi Memorial Institute for Medical Research, University of Ghana, Legon.
Eric Kyei-BaafourNoguchi Memorial Institute for Medical Research, University of Ghana, Legon.
Lars HviidCenter for Medical Parasitology at Department of Immunology and Microbiology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
University of Ghana · GHUniversity of Copenhagen · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Plasmodium falciparum parasites causing placental malaria express the VAR2CSA type of the clonally variant antigen family erythrocyte membrane protein 1 (PfEMP1). This enables evasion of preexisting immunity and results in placental accumulation of infected erythrocytes. We present data on seasonal variation in levels of VAR2CSA-specific immunoglobulin G (IgG) and IgG specific for a placental malaria-unrelated PfEMP1 protein among Ghanaian women at their first antenatal visit. Our results indicate that placental malaria does not require recent exposure to infected mosquitoes, in contrast to malaria in general. This has implications for the impact of insecticide-treated bed nets on placental malaria incidence and for antenatal care in woman with preexisting immunity.

Indexed as

AdultFemaleGenotypeGhanaHumansIncidenceMalaria, FalciparumPlacenta DiseasesPlasmodium falciparumPregnancyPregnancy Complications, InfectiousProtozoan ProteinsSeasonsYoung Adulterythrocyte membrane protein 1, Plasmodium falciparumProtozoan Proteins

Identifiers

PMID29579263
PMCPMC6009667
OpenAlexW2808861574

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.