Evidence map›Paper›PMID 29579150›Full record

ArticleCardiovascular research2018

Dietary fat is a key determinant in balancing mitochondrial dynamics in heart failure: a novel mechanism underlying the obesity paradox.

Matteo De Rosa, Jessica Gambardella, Jun Shu, Gaetano Santulli

Open access · bronzeAbstract readEditorialComment
In one paragraph

Article in Cardiovascular research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 20 citations in OpenAlex.

  1. Decoding the coronary paradox of obesity: not all fat is equal!International journal of cardiology. Heart & vasculature · 2025
    Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Observational
  8. Article
  9. Heart failure in diabetes.Metabolism: clinical and experimental · 2021
    Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Diabetes, body fat, skeletal muscle, and hypertension: The ominous chiasmus?Journal of clinical hypertension (Greenwich, Conn.) · 2019
    Article
  15. The Impact of Obesity on the Cardiovascular System.Journal of diabetes research · 2018
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Matteo De RosaDepartment of Advanced Biomedical Sciences, 'Federico II' University of Naples, Azienda Ospedaliera Universitaria Policlinico, Via Sergio Pansini, 5, Naples 80131, Italy.
Jessica GambardellaDepartment of Advanced Biomedical Sciences, 'Federico II' University of Naples, Azienda Ospedaliera Universitaria Policlinico, Via Sergio Pansini, 5, Naples 80131, Italy.
Jun ShuDepartment of Medicine, Albert Einstein College of Medicine, Montefiore University Hospital, 1300 Morris Park Avenue, Forchheimer Medical Science Building, New York, NY 10461, USA.
Gaetano SantulliDepartment of Advanced Biomedical Sciences, 'Federico II' University of Naples, Azienda Ospedaliera Universitaria Policlinico, Via Sergio Pansini, 5, Naples 80131, Italy.
Albert Einstein College of Medicine · US

Funding

Targeting intracellular calcium leak as novel therapy for diabetesR00DK107895 · NIDDK · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI SANTULLI, GAETANO · 2018 to 2020
$741k
NIDDK NIH HHS R00 DK107895
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Heart FailureOptic Atrophy, Autosomal DominantDietary FatsFatty AcidsHumansMitochondrial DynamicsObesityDietary FatsFatty Acids

Identifiers

PMID29579150
PMCPMC5967494
OpenAlexW2791543684

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.