Evidence map›Paper›PMID 29579123›Full record

ArticlePloS one2018

Temporal changes in electrocardiographic frontal QRS-T angle and survival in patients with heart failure.

Israel Gotsman, Ayelet Shauer, Yair Elizur, Donna R Zwas, Chaim Lotan, Andre Keren

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In one paragraph

Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Israel GotsmanHeart Failure Center, Heart Institute, Hadassah University Hospital, Jerusalem, Israel.ORCID 0000-0001-9608-2298
Ayelet ShauerHeart Failure Center, Heart Institute, Hadassah University Hospital, Jerusalem, Israel.
Yair ElizurHeart Failure Center, Heart Institute, Hadassah University Hospital, Jerusalem, Israel.
Donna R ZwasHeart Failure Center, Heart Institute, Hadassah University Hospital, Jerusalem, Israel.
Chaim LotanHeart Failure Center, Heart Institute, Hadassah University Hospital, Jerusalem, Israel.
Andre KerenHeart Failure Center, Heart Institute, Hadassah University Hospital, Jerusalem, Israel.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHeart failure (HF) is associated with considerable mortality. The electrocardiographic frontal QRS-T angle is a simple parameter to measure, reflects changes in the direction of the repolarization sequence and predicts outcome in patients with HF. Data regarding temporal changes in the frontal QRS-T angle in patients with HF and its impact on outcome is limited.

aimTo evaluate temporal changes in the frontal QRS-T angle and its effect on survival in patients with HF.

methodsBaseline and follow-up QRS-T angle were calculated from the frontal QRS and T axis of the 12-lead surface electrocardiogram. Patients were followed for survival.

results2,929 HF patients were evaluated. Median interval between baseline ECG and follow-up ECG was 895 days, median follow-up time was 1526 days. Overall, the QRS-T angle tended to be stable, with minor changes in the angle over time. The median QRS-T angle change was +3° (IQR -19° to +30°). Overall survival during follow-up was 60%. Cox regression analysis after adjustment for significant predictors demonstrated that the QRS-T angle was an incremental predictor of increased mortality. A widening of the QRS-T angle during follow-up was independently associated with an increase in mortality, evident with an increase of the QRS-T angle difference above 0° (P<0.0001 for the adjusted model).

conclusionQRS-T angle is relatively stable in patients with HF and is a powerful predictor of outcome. Widening of the QRS-T angle has predictive value and is an ominous sign.

Indexed as

ElectrocardiographyAgedAged, 80 and overBiomarkersFemaleFollow-Up StudiesHeart FailureHumansKaplan-Meier EstimateMaleMiddle AgedPrognosisRegression AnalysisRisk FactorsTime FactorsBiomarkers

Identifiers

PMID29579123
PMCPMC5868814

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.