ArticleEnvironmental health perspectives2018
House Dust Endotoxin Association with Chronic Bronchitis and Emphysema.
Article in Environmental health perspectives, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 36 citations in OpenAlex.
- Indoor dust, immune activation, and household exposure risk after Hurricane Maria: a two-year pilot prospective cohort study in Puerto Rico.Journal of exposure science & environmental epidemiology · 2026Article
- Shape of the association between endotoxin in school dust and children's lung function.ERJ open research · 2025Article
- Disinfection byproducts in US drinking water and cancer mortality.International journal of environmental health research · 2025Article
- Machine learning prediction model with shap interpretation for chronic bronchitis risk assessment based on heavy metal exposure: a nationally representative study.BMC pulmonary medicine · 2025Article
- Association between house dust endotoxin and kidney injury: findings from the national health and nutrition examination survey (NHANES) 2005-2006.International urology and nephrology · 2024Article
- Associations between ethylene oxide exposure and chronic bronchitis: results from the NHANES 2013-2018.Frontiers in public health · 2024Article
- Influence of Rural Environmental Factors in Asthma.Immunology and allergy clinics of North America · 2022Review
- Lung function of primary cooks using LPG or biomass and the effect of particulate matter on airway epithelial barrier integrity.Environmental research · 2020Article
- Role of pulmonary function and FeNO detection in early screening of patients with ACO.Experimental and therapeutic medicine · 2020Article
- Validation of Questionnaire-based Case Definitions for Chronic Obstructive Pulmonary Disease.Epidemiology (Cambridge, Mass.) · 2020Article
- Endotoxin clustering with allergens in house dust and asthma outcomes in a U.S. national study.Environmental health : a global access science source · 2020Article
- Prevalence and Risk Factors of Chronic Obstructive Pulmonary Disease Among Agriculturists in a Rural Community, Central Thailand.International journal of chronic obstructive pulmonary disease · 2020Article
- Household endotoxin reduction in the Louisa Environmental Intervention Project for rural childhood asthma.Indoor air · 2020Article
- Synergistic Association of House Endotoxin Exposure and Ambient Air Pollution with Asthma Outcomes.American journal of respiratory and critical care medicine · 2019Article
- Prevalence and features of asthma-COPD overlap in the United States 2007-2012.The clinical respiratory journal · 2018Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundEndotoxin has been reported to be associated with chronic bronchitis or emphysema (CBE) at high occupational exposures. However, whether levels found in domestic environments have similar effects is unknown.
objectivesWe aimed to study the association between house dust endotoxin and CBE in a sample representative of the U.S. population.
methodsWe analyzed data from 3,393 participants ≥20 y old from the National Health and Nutrition Examination Survey (NHANES) 2005-2006. House dust from bedding and from bedroom floors was analyzed for endotoxin content. NHANES participants received questionnaires and underwent examination as well as extensive laboratory testing. Logistic regression was used to examine the association of endotoxin levels with CBE diagnosis and symptoms, adjusting for covariates. The survey design and weights were applied so that estimates were nationally representative and so that statistical inferences were made appropriately.
resultsThe median endotoxin concentration in house dust was 14.61 EU/mg dust, and CBE was reported by 8.2% of participants. In the adjusted analysis, one unit (EU/mg) increase in log
conclusionsIn a population-based sample of U.S. adults, endotoxin levels in homes were associated with a self-reported history of CBE diagnosis and chronic bronchitis symptoms, with stronger associations among people sensitized to inhalant allergens. https://doi.org/10.1289/EHP2452.
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