Evidence map›Paper›PMID 29578059›Full record

ReviewNitric oxide : biology and chemistry2018

The effect of the electrophilic fatty acid nitro-oleic acid on TRP channel function in sensory neurons.

Jonathan M Beckel, William C de Groat

Abstract readReview
In one paragraph

Review in Nitric oxide : biology and chemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Trial
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Jonathan M BeckelDepartment of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA. Electronic address: jmbeckel@pitt.edu.
William C de GroatDepartment of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA.
University of Pittsburgh · US

Funding

Urothelium in Detrusor OveractivityP01DK093424 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI DEGROAT, WILLIAM C · 2013 to 2017
$7.9M
PDE5 Inhibition of Afferents and Interstitial Cells in Overactive Mouse BladdersR01DK098361 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BIRDER, LORI A, KANAI, ANTHONY JOHN · 2014 to 2024
$5.7M
Parasympathetic and sympathetic mechanisms underlying bladder nociceptionR01DK111382 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BECKEL, JONATHAN M · 2017 to 2020
$1.4M
Role of Pannexins in Urinary Bladder PathologyK01DK106115 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BECKEL, JONATHAN M · 2015 to 2017
$362k
The Lysosome as an ATP Source in the Urothelium and its Role in PathologyR03DK114492 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BECKEL, JONATHAN M · 2017 to 2018
$156k
NIDDK NIH HHS K01 DK106115NIDDK NIH HHS P01 DK093424NIDDK NIH HHS R01 DK098361NIDDK NIH HHS R01 DK111382NIDDK NIH HHS R03 DK114492
6 · The paper itself

Abstract

Nitro-oleic acid (NO

Indexed as

Afferent nervesAllyl isothiocyanate (AITC)CapsaicinDorsal root ganglia (DRG)Electrophilic fatty acidsNitro-oleic acidTransient receptor potential ankyrin 1 (TRPA1)Transient receptor potential canonical (TRPC)Transient receptor potential vanilloid 1 (TRPV1)Urinary bladder

Identifiers

PMID29578059
PMCPMC6151181
OpenAlexW2792174898

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.