Evidence map›Paper›PMID 29577795›Full record

ArticleThe International journal of artificial organs2018

Regional citrate-calcium anticoagulation during polymyxin-B hemoperfusion: A case series.

Francesco Forfori, Etrusca Brogi, Anna Sidoti, Martina Giraudini, Gianpaola Monti, Nadia Zarrillo, Vincenzo Cantaluppi, Claudio Ronco

Open access · hybridAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in The International journal of artificial organs, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Observational
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Francesco Forfori1 Department of Anesthesia and Intensive Care, University of Pisa, Pisa, Italy.
Etrusca Brogi1 Department of Anesthesia and Intensive Care, University of Pisa, Pisa, Italy.
Anna Sidoti1 Department of Anesthesia and Intensive Care, University of Pisa, Pisa, Italy.
Martina Giraudini1 Department of Anesthesia and Intensive Care, University of Pisa, Pisa, Italy.
Gianpaola Monti2 Department of Anesthesiology and Intensive Care, Azienda Ospedaliera Niguarda Cà Granda, Milano, Italy.
Nadia Zarrillo3 Department of Anesthesia and Intensive Care, Hospital Sant'Anna and San Sebastiano Caserta, Caserta, Italy.
Vincenzo Cantaluppi4 Division of Nephrology and Transplantation, Department of Translational Medicine, University of Eastern Piedmont (UPO), Novara, Italy.
Claudio Ronco5 Department of Nephrology, Dialysis and Transplantation, International Renal Research Institute of Vicenza (IRRIV), San Bortolo Hospital, Vicenza, Italy.
University of Pisa · ITAzienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda · ITInternational Renal Research Institute of Vicenza · ITOspedale Sant'Anna · ITUniversità degli Studi del Piemonte Orientale “Amedeo Avogadro” · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionSo far, only heparin-based anticoagulation has been proposed during polymyxin-B hemoperfusion. However, postsurgical septic patients can be at high risk of bleeding due to either surgical complications or septic coagulation derangement. Consequently, heparin should not represent in some cases the anticoagulation regimen of choice in this type of patients. METHODS AND

resultsWe present a case series of four postsurgical septic patients treated with polymyxin-B hemoperfusion using regional citrate anticoagulation. All the treatments were performed without complications. During each treatment, there were no episodes of filter clotting, no bleeding, and no metabolic complications for any of the patients.

conclusionTo our knowledge, this is the second published report on the use of citrate anticoagulation during polymyxin-B hemoperfusion. Our case series continued to show that regional citrate anticoagulation regimen is feasible and safe during polymyxin-B hemoperfusion treatment in postsurgical septic patients.

Indexed as

AgedAnti-Bacterial AgentsAnticoagulantsBlood CoagulationCitric AcidFemaleHemoperfusionHumansMaleMiddle AgedPolymyxin BShock, SepticTreatment OutcomeAnti-Bacterial AgentsAnticoagulantsCitric AcidPolymyxin Bcitrate anticoagulationPolymixin-B hemoperfusionseptic coagulation derangementseptic shock

Identifiers

PMID29577795
PMCPMC6159843
OpenAlexW2790036021

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.