Evidence map›Paper›PMID 29577619›Full record

ReviewJournal of cellular and molecular medicine2018

Cellular and molecular mechanisms of vitamin D in food allergy.

Ashlyn Poole, Yong Song, Helen Brown, Prue H Hart, Guicheng Brad Zhang

Open access · goldAbstract readReview
In one paragraph

Review in Journal of cellular and molecular medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 65 citations in OpenAlex.

  1. Review
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  9. [Risk factors for cow's milk protein allergy in infants: a multicenter prospective nested case-control study].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2024
    Article
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  17. Cord blood 25(OH)DThe World Allergy Organization journal · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Ashlyn PooleSchool of Public Health, Curtin University, Bentley, WA, Australia.ORCID 0000-0002-9949-3380
Yong SongSchool of Public Health, Curtin University, Bentley, WA, Australia.
Helen BrownSchool of Public Health, Curtin University, Bentley, WA, Australia.
Prue H HartTelethon Kids Institute, The University of Western Australia, Crawley, WA, Australia.
Guicheng Brad ZhangSchool of Public Health, Curtin University, Bentley, WA, Australia.
Curtin University · AUThe Kids Research Institute Australia · AUThe University of Western Australia · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Food allergies are becoming increasingly prevalent, especially in young children. Epidemiological evidence from the past decade suggests a role of vitamin D in food allergy pathogenesis. Links have been made between variations in sunlight exposure, latitude, birth season and vitamin D status with food allergy risk. Despite the heightened interest in vitamin D in food allergies, it remains unclear by which exact mechanism(s) it acts. An understanding of the roles vitamin D plays within the immune system at the cellular and genetic levels, as well as the interplay between the microbiome and vitamin D, will provide insight into the importance of the vitamin in food allergies. Here, we discuss the effect of vitamin D on immune cell maturation, differentiation and function; microbiome; genetic and epigenetic regulation (eg DNA methylation); and how these processes are implicated in food allergies.

Indexed as

DNA MethylationEpigenesis, GeneticFood HypersensitivityGastrointestinal MicrobiomeHumansImmunity, InnateImmunoglobulin EVitamin DVitamin D DeficiencyImmunoglobulin EVitamin Depigeneticsfood allergygeneticsmicrobiomevitamin D

Identifiers

PMID29577619
PMCPMC6010899
OpenAlexW2792759613

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.