Evidence map›Paper›PMID 29577375›Full record

ArticleJournal of neuroscience research2018

Ca2+/calmodulin-dependent protein kinase II and Dimethyl Sulfoxide affect the sealing frequencies of transected hippocampal neurons.

Andrew D Poon, Sarah H McGill, Solomon Raju Bhupanapadu Sunkesula, Zachary S Burgess, Patrick J Dunne, Edward E Kang, George D Bittner

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of neuroscience research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Andrew D PoonDepartment of Neuroscience, The University of Texas at Austin, 2415 Speedway Austin, TX, 78712, USA.ORCID 0000-0001-8037-4501
Sarah H McGillDepartment of Neuroscience, The University of Texas at Austin, 2415 Speedway Austin, TX, 78712, USA.ORCID 0000-0001-8637-3219
Solomon Raju Bhupanapadu SunkesulaDepartment of Neuroscience, The University of Texas at Austin, 2415 Speedway Austin, TX, 78712, USA.
Zachary S BurgessDepartment of Neuroscience, The University of Texas at Austin, 2415 Speedway Austin, TX, 78712, USA.
Patrick J DunneDepartment of Neuroscience, The University of Texas at Austin, 2415 Speedway Austin, TX, 78712, USA.
Edward E KangDepartment of Neuroscience, The University of Texas at Austin, 2415 Speedway Austin, TX, 78712, USA.
George D BittnerDepartment of Neuroscience, The University of Texas at Austin, 2415 Speedway Austin, TX, 78712, USA.ORCID 0000-0002-5610-6264
The University of Texas at Austin · US

Funding

A novel bioengineered technique to rapidly and permanently repair cut PNS nervesR01NS081063 · NINDS · UNIVERSITY OF TEXAS AT AUSTIN · PI BITTNER, GEORGE DAVIS · 2012 to 2016
$1.7M
NINDS NIH HHS R01 NS081063
6 · The paper itself

Abstract

Traumatic injury often results in axonal severance, initiating obligatory Wallerian degeneration of distal segments, whereas proximal segments often survive. Calcium ion (Ca

Indexed as

Accessory Nerve InjuriesAnimalsAxon Initial SegmentAxotomyBenzenesulfonamidesBenzylaminesCalciumCalcium-Calmodulin-Dependent Protein Kinase Type 2Calcium SignalingCell LineDimethyl SulfoxideHippocampusModels, NeurologicalNeuronsPeptidesProtein Kinase InhibitorsBenzenesulfonamidesBenzylaminesCalciumCalcium-Calmodulin-Dependent Protein Kinase Type 2Dimethyl SulfoxideKN 93PeptidesProtein Kinase InhibitorsSulfonamidestatCN21 peptideaxolemmal sealingaxotomyCaMKIIDMSOmembrane repairRRID: CVCL_0154

Identifiers

PMID29577375
PMCPMC5980716
OpenAlexW2790085274

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.