Evidence map›Paper›PMID 29577037›Full record

ReviewJournal of clinical and translational hepatology2018

Chylous Ascites: A Review of Pathogenesis, Diagnosis and Treatment.

Richa Bhardwaj, Haleh Vaziri, Arun Gautam, Enrique Ballesteros, David Karimeddini, George Y Wu

Open access · diamondAbstract readReview
In one paragraph

Review in Journal of clinical and translational hepatology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 146 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
146citing papers in PubMed, 4 pooled it
9.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

146 citing papers in PubMed, 4 syntheses or guidelines pooled it, 262 citations in OpenAlex.

  1. Guideline
  2. [Guidelines on the management of ascites in cirrhosis (2023 version)].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2023
    Guideline
  3. Incidence and risk factors for Chyle leak after pancreatic surgery for cancer: A comprehensive systematic review.European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology · 2022
    Pooled it
  4. Guideline
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Dietary interventionsWorld journal of transplantation · 2025
    Article
  19. Article
  20. Article

86 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Richa BhardwajDepartment of Medicine, Division of Gastroenterology-Hepatology, UCONN Health, Farmington, CT, USA.
Haleh VaziriDepartment of Medicine, Division of Gastroenterology-Hepatology, UCONN Health, Farmington, CT, USA.
Arun GautamDepartment of Medicine, Division of Gastroenterology-Hepatology, UCONN Health, Farmington, CT, USA.
Enrique BallesterosDepartment of Pathology and Lab Medicine, UCONN Health, Farmington, CT, USA.
David KarimeddiniDepartment of Diagnostic Imaging and Therapeutics, UCONN Health, Farmington, CT, USA.
George Y WuDepartment of Medicine, Division of Gastroenterology-Hepatology, UCONN Health, Farmington, CT, USA.
UConn Health · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chylous ascites (CA) is a rare form of ascites that results from the leakage of lipid-rich lymph into the peritoneal cavity. This usually occurs due to trauma and rupture of the lymphatics or increased peritoneal lymphatic pressure secondary to obstruction. The underlying etiologies for CA have been classified as traumatic, congenital, infectious, neoplastic, postoperative, cirrhotic or cardiogenic. Since malignancy and cirrhosis account for about two-thirds of all the cases of CA in Western countries, in this article we have attempted to reclassify CA based on portal and non-portal etiologies. The diagnosis of CA is based on the distinct characteristic of the ascitic fluid which includes a milky appearance and a triglyceride level of >200 mg/dL. The management consists of identifying and treating the underlying disease process, dietary modification, and diuretics. Some studies have also supported the use of agents such as orlistat, somatostatin, octreotide and etilefrine. Paracentesis and surgical interventions in the form of transjugular intrahepatic portosystemic shunt (commonly known as TIPS), peritoneal shunt, angiography with embolization of a leaking vessel, and laparotomy remain as treatment options for cases refractory to medical management.

Indexed as

Ascitic fluidChylous ascitesCirrhosisLymphatic systemPortal hypertension

Identifiers

PMID29577037
PMCPMC5863006
OpenAlexW2772136819

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.