ArticleTranslational vision science & technology2018
Retinal Vessel Diameters Change Within 1 Hour of Intracranial Pressure Lowering.
Article in Translational vision science & technology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed, 1 citations in OpenAlex.
- Retinal vessel diameter changes after 6 months of treatment in the Idiopathic Intracranial Hypertension Treatment Trial.The British journal of ophthalmology · 2020Trial
- Association of papilledema severity with retinal vessel tortuosity in idiopathic intracranial hypertension.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026Article
- Diagnosis of High Intracranial Pressure by Non-Optic Nerve Retinal Image Features.Translational vision science & technology · 2026Article
- Oculomics in the ICU: Retinal vessel autoregulation as a real-time biomarker for cerebral perfusion pressure.Brain & spine · 2026Article
- Non-invasive fundoscopy as a tool to estimate intracranial pressure: a large animal model.Acta neurochirurgica · 2025Article
- Utilizing retinal arteriole/venule ratio to estimate intracranial pressure.Acta neurochirurgica · 2024Article
- Non-invasive assessment of intracranial pressure through the eyes: current developments, limitations, and future directions.Frontiers in neurology · 2024Review
- Variability of Retinal Vessel Tortuosity Measurements Using a Semiautomated Method Applied to Fundus Images in Subjects With Papilledema.Translational vision science & technology · 2021Article
- Retinal Vein Changes as a Biomarker to Guide Diagnosis and Management of Elevated Intracranial Pressure.Frontiers in neurology · 2021Review
- A new novel method for assessing intracranial pressure using non-invasive fundus images: a pilot study.Scientific reports · 2020Observational
- An Update on Imaging in Idiopathic Intracranial Hypertension.Frontiers in neurology · 2020Review
- Methods for Quantifying Optic Disc Volume and Peripapillary Deflection Volume Using Radial Optical Coherence Tomography Scans and Association With Intracranial Pressure.Frontiers in neurology · 2019Article
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
Abstract
purposeWe tested the hypotheses that retinal venule diameter (Dv) is associated with baseline intracranial pressure (ICP) level and that Dv is reduced shortly after ICP lowering.
methodsDv and arteriole diameter (Da) were extracted from scanning laser ophthalmoscopic images in 40 eyes of 20 adult human subjects (10 with and 10 without papilledema) immediately before and after measurement of ICP (range, 10-55 cm H
resultsTest-retest variability of diameter measurements ranged from 0.1 to 2.9 μm (0.1%-2.72%). Neither Da nor Dv pre-LP was associated with baseline ICP level (
conclusionsRetina arteriole and venule diameters change immediately following ICP lowering. The direction of change is dependent on the initial ICP; both increased in subjects with high ICP and both decreased in subjects with normal ICP. TRANSLATIONAL RELEVANCE: The relationship between initial ICP and direction of retinal vessel size change following ICP lowering suggests a potential effect of ICP on cerebral and ocular hemodynamics that is relevant when considering the use of retinal vessel measurements as a clinical marker of ICP change.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.