Evidence map›Paper›PMID 29576853›Full record

ArticleOxidative medicine and cellular longevity2018

Quercetin Prevents Diastolic Dysfunction Induced by a High-Cholesterol Diet: Role of Oxidative Stress and Bioenergetics in Hyperglycemic Rats.

Rodrigo L Castillo, Emilio A Herrera, Alejandro Gonzalez-Candia, Marjorie Reyes-Farias, Nicole de la Jara, Juan Pedro Peña, Catalina Carrasco-Pozo

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 66 citations in OpenAlex.

  1. Article
  2. Pequi (Antioxidants (Basel, Switzerland) · 2025
    Article
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  7. Role of Quercetin in Diabetic Cardiomyopathy.Plants (Basel, Switzerland) · 2024
    Review
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  9. Review
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  11. Review
  12. Article
  13. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Rodrigo L CastilloPathophysiology Program, ICBM, Faculty of Medicine, University of Chile, Av. Salvador 486, Providencia, 7500922 Santiago, Chile.ORCID 0000-0002-0549-1326
Emilio A HerreraPathophysiology Program, ICBM, Faculty of Medicine, University of Chile, Av. Salvador 486, Providencia, 7500922 Santiago, Chile.ORCID 0000-0002-6342-085X
Alejandro Gonzalez-CandiaPathophysiology Program, ICBM, Faculty of Medicine, University of Chile, Av. Salvador 486, Providencia, 7500922 Santiago, Chile.ORCID 0000-0001-8429-367X
Marjorie Reyes-FariasDepartment of Nutrition, Faculty of Medicine, University of Chile, Santiago, Chile.
Nicole de la JaraDepartment of Nutrition, Faculty of Medicine, University of Chile, Santiago, Chile.
Juan Pedro PeñaUniversidad de Viña del Mar, Región de Valparaíso, Chile.
Catalina Carrasco-PozoDepartment of Nutrition, Faculty of Medicine, University of Chile, Santiago, Chile.ORCID 0000-0002-2029-2114
University of Chile · CLGriffith University · AUViña del Mar University · CL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alterations in cardiac energy metabolism play a key role in the pathogenesis of diabetic cardiomyopathy. Hypercholesterolemia associated with bioenergetic impairment and oxidative stress has not been well characterized in the cardiac function under glycemic control deficiency conditions. This work aimed to determine the cardioprotective effects of

Indexed as

AnimalsCholesterolDietEnergy MetabolismHeart MurmursHypercholesterolemiaHyperglycemiaMaleOxidative StressQuercetinRandom AllocationRatsRats, WistarCholesterolQuercetin

Identifiers

PMID29576853
PMCPMC5821945
OpenAlexW2783388547

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.