Evidence map›Paper›PMID 29576847›Full record

ArticleOxidative medicine and cellular longevity2018

Differentiation of Promonocytic U937 Cells to Monocytes Is Associated with Reduced Mitochondrial Transport of Ascorbic Acid.

Maddalena Scotti, Mara Fiorani, Andrea Guidarelli, Orazio Cantoni

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Maddalena ScottiDepartment of Biomolecular Sciences University of Urbino "Carlo Bo", 61029 Urbino, Italy.
Mara FioraniDepartment of Biomolecular Sciences University of Urbino "Carlo Bo", 61029 Urbino, Italy.
Andrea GuidarelliDepartment of Biomolecular Sciences University of Urbino "Carlo Bo", 61029 Urbino, Italy.
Orazio CantoniDepartment of Biomolecular Sciences University of Urbino "Carlo Bo", 61029 Urbino, Italy.ORCID 0000-0002-7182-802X
University of Urbino · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Growth of promonocytic U937 cells in the presence of DMSO promotes their differentiation to monocytes. After 4 days of culture in differentiating medium, these cells ceased to proliferate, displayed downregulated ryanodine receptor expression, and responded to specific stimuli with enhanced NADPH-oxidase-derived superoxide formation or cytosolic phospholipase A

Indexed as

Ascorbic AcidBiological TransportCell DifferentiationDimethyl SulfoxideHumansMitochondriaMonocytesPeroxynitrous AcidSodium-Coupled Vitamin C TransportersU937 CellsAscorbic AcidDimethyl SulfoxidePeroxynitrous AcidSLC23A2 protein, humanSodium-Coupled Vitamin C Transporters

Identifiers

PMID29576847
PMCPMC5822789
OpenAlexW2787122303

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.