Evidence map›Paper›PMID 29576845›Full record

ArticleOxidative medicine and cellular longevity2018

Immunomodulatory Effects of Diterpene Quinone Derivatives from the Roots of

K Becker, S Schwaiger, B Waltenberger, D Fuchs, C K Pezzei, H Schennach, H Stuppner, J M Gostner

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Anti-inflammatory activities ofFrontiers in pharmacology · 2022
    Article
  7. Review
  8. Abietane Diterpenoids from the Hairy Roots ofMolecules (Basel, Switzerland) · 2021
    Article
  9. Immunomodulatory and Anticancer Activities ofPlants (Basel, Switzerland) · 2021
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

K BeckerDivision of Biological Chemistry, Biocenter, Medical University of Innsbruck, Innsbruck, Austria.
S SchwaigerInstitute of Pharmacy/Pharmacognosy and Center for Molecular Biosciences Innsbruck (CMBI), University of Innsbruck, Innsbruck, Austria.
B WaltenbergerInstitute of Pharmacy/Pharmacognosy and Center for Molecular Biosciences Innsbruck (CMBI), University of Innsbruck, Innsbruck, Austria.
D FuchsDivision of Biological Chemistry, Biocenter, Medical University of Innsbruck, Innsbruck, Austria.ORCID 0000-0003-1627-9563
C K PezzeiInstitute of Pharmacy/Pharmacognosy and Center for Molecular Biosciences Innsbruck (CMBI), University of Innsbruck, Innsbruck, Austria.
H SchennachCentral Institute of Blood Transfusion and Immunology, University Hospital of Innsbruck, Innsbruck, Austria.
H StuppnerInstitute of Pharmacy/Pharmacognosy and Center for Molecular Biosciences Innsbruck (CMBI), University of Innsbruck, Innsbruck, Austria.ORCID 0000-0001-8862-0201
J M GostnerDivision of Medical Biochemistry, Biocenter, Medical University of Innsbruck, Innsbruck, Austria.ORCID 0000-0003-1532-5177
Universität Innsbruck · ATInnsbruck Medical University · ATUniversity Hospital Innsbruck · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Several phytochemicals were shown to interfere with redox biology in the human system. Moreover, redox biochemistry is crucially involved in the orchestration of immunological cascades. When screening for immunomodulatory compounds, the two interferon gamma- (IFN-

Indexed as

Cells, CulturedDiterpenesHumansImmunologic FactorsKynurenineLamiaceaeLeukocytes, MononuclearNeopterinPlant ExtractsPlant RootsQuinonesTryptophanDiterpenesImmunologic FactorsKynurenineNeopterinPlant ExtractsQuinonesTryptophan

Identifiers

PMID29576845
PMCPMC5821946
OpenAlexW2783971109

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.