Evidence map›Paper›PMID 29576629›Full record

ArticleGeburtshilfe und Frauenheilkunde2018

Update Breast Cancer 2018 (Part 1) - Primary Breast Cancer and Biomarkers.

Florin-Andrei Taran, Andreas Schneeweiss, Michael P Lux, Wolfgang Janni, Andreas D Hartkopf, Naiba Nabieva, Friedrich Overkamp, Hans-Christian Kolberg, Peyman Hadji, Hans Tesch and 12 more

Open access · hybridAbstract read
In one paragraph

Article in Geburtshilfe und Frauenheilkunde, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 23 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 13 institutions in 1 country.

Florin-Andrei TaranDepartment of Obstetrics and Gynecology, University of Tübingen, Tübingen, Germany.
Andreas SchneeweissNational Center for Tumor Diseases, Division Gynecologic Oncology, University Hospital Heidelberg, Heidelberg, Germany.
Michael P LuxErlangen University Hospital, Department of Gynecology and Obstetrics, Comprehensive Cancer Center Erlangen-EMN, Friedrich-Alexander University Erlangen-Nuremberg, Erlangen, Germany.
Wolfgang JanniDepartment of Gynecology and Obstetrics, Ulm University Hospital, Ulm, Germany.
Andreas D HartkopfDepartment of Obstetrics and Gynecology, University of Tübingen, Tübingen, Germany.
Naiba NabievaErlangen University Hospital, Department of Gynecology and Obstetrics, Comprehensive Cancer Center Erlangen-EMN, Friedrich-Alexander University Erlangen-Nuremberg, Erlangen, Germany.
Friedrich OverkampOncoConsult Hamburg GmbH, Hamburg, Germany.
Hans-Christian KolbergDepartment of Gynecology and Obstetrics, Marienhospital Bottrop, Bottrop, Germany.
Peyman HadjiDepartment of Bone Oncology, Nordwest Hospital, Frankfurt, Germany.
Hans TeschOncology Practice at Bethanien Hospital Frankfurt, Frankfurt, Germany.
Achim WöckelDepartment of Gynecology and Obstetrics, University Hospital Würzburg, Würzburg, Germany.
Johannes EttlDepartment of Obstetrics and Gynecology, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany.
Diana LüftnerCharité University Hospital, Berlin, Campus Benjamin Franklin, Department of Hematology, Oncology and Tumour Immunology, Berlin, Germany.
Markus WallwienerDepartment of Obstetrics and Gynecology, University of Heidelberg, Heidelberg, Germany.
Volkmar MüllerDepartment of Gynecology, Hamburg-Eppendorf University Medical Center, Hamburg, Germany.
Matthias W BeckmannErlangen University Hospital, Department of Gynecology and Obstetrics, Comprehensive Cancer Center Erlangen-EMN, Friedrich-Alexander University Erlangen-Nuremberg, Erlangen, Germany.
Erik BellevilleClinSol GmbH & Co KG, Würzburg, Germany.
Diethelm WallwienerDepartment of Obstetrics and Gynecology, University of Tübingen, Tübingen, Germany.
Sara Y BruckerDepartment of Obstetrics and Gynecology, University of Tübingen, Tübingen, Germany.
Peter A FaschingErlangen University Hospital, Department of Gynecology and Obstetrics, Comprehensive Cancer Center Erlangen-EMN, Friedrich-Alexander University Erlangen-Nuremberg, Erlangen, Germany.
Tanja N FehmDepartment of Gynecology and Obstetrics, University Hospital Düsseldorf, Düsseldorf, Germany.
Florian SchützDepartment of Obstetrics and Gynecology, University of Heidelberg, Heidelberg, Germany.
Comprehensive Cancer Center Erlangen · DEUniversity of Tübingen · DEHeidelberg University · DECardiovascular Center Bethanien · DECharité - Universitätsmedizin Berlin · DEHeinrich Heine University Düsseldorf · DEKlinikum rechts der Isar · DEKrankenhaus Nordwest · DEMarienhospital Bottrop · DEUniversität Hamburg · DEUniversitätsklinikum Würzburg · DEUniversity Hospital Heidelberg · DEUniversity Hospital Ulm · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This summary provides an overview of how new therapies or new aspects of established therapies relate to the latest findings. Neoadjuvant therapy, local therapy, new aspects of systemic therapy, and prognostic and predictive factors are presented. In the neoadjuvant setting, the association between pathological complete response (pCR) and prognosis is still of interest as is the identification of new molecular predictors for new therapies such as CDK4/6 inhibitors. As regards surgical treatment, the target is still to reduce the aggressiveness of surgery. To achieve this, a better understanding particularly of ductal carcinoma in situ is required. With regard to systemic therapy, more data on the best combinations and therapy sequences for existing therapies is available. Finally, the use of prognostic and predictive factors may help to avoid overtreatment and ensure that patients only receive therapies which have been shown to be effective for their specific condition and have fewer side effects.

Indexed as

breast cancerlocal recurrencepredictive factorsprognostic factorstreatment/therapytrials

Identifiers

PMID29576629
PMCPMC5862549
OpenAlexW2789588170

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.