Evidence map›Paper›PMID 29576602›Full record

ArticleJournal of epidemiology2018

Association of Adiponectin With Cancer and All-Cause Mortality in a Japanese Community-Dwelling Elderly Cohort: A Case-Cohort Study.

Reiji Kojima, Shigekazu Ukawa, Wenjing Zhao, Koji Suzuki, Hiroya Yamada, Kazuyo Tsushita, Takashi Kawamura, Satoe Okabayashi, Kenji Wakai, Hisashi Noma and 2 more

Open access · goldAbstract read
In one paragraph

Article in Journal of epidemiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 7 institutions in 1 country.

Reiji KojimaDepartment of Public Health, Hokkaido University Graduate School of Medicine.ORCID 0000-0002-9712-889X
Shigekazu UkawaDepartment of Public Health, Hokkaido University Graduate School of Medicine.ORCID 0000-0003-4084-1720
Wenjing ZhaoDepartment of Public Health, Hokkaido University Graduate School of Medicine.
Koji SuzukiFaculty of Medical Technology, Fujita Health University School of Health Sciences.ORCID 0000-0002-3235-9558
Hiroya YamadaDepartment of Hygiene, Fujita Health University School of Medicine.
Kazuyo TsushitaComprehensive Health Science Center, Aichi Health Promotion Foundation.
Takashi KawamuraKyoto University Health Service.
Satoe OkabayashiKyoto University Health Service.
Kenji WakaiDepartment of Preventive Medicine, Nagoya University Graduate School of Medicine.
Hisashi NomaDepartment of Data Science, The Institute of Statistical Mathematics.
Masahiko AndoCenter for Advanced Medicine and Clinical Research, Hospital, Nagoya University.
Akiko TamakoshiDepartment of Public Health, Hokkaido University Graduate School of Medicine.ORCID 0000-0002-9761-3879
Hokkaido University · JPFujita Health University · JPKyoto University · JPAichi Health Promotion Foundation · JPNagoya University · JPNagoya University Hospital · JPThe Institute of Statistical Mathematics · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMost studies of plasma adiponectin (APN) and mortality among community-dwelling elderly focus on cardiovascular disease, but data on the relationship between plasma APN and cancer mortality is exiguous. We investigated whether APN is associated with cancer mortality in community-dwelling elderly people.

methodsWe conducted a case-cohort study within the New Integrated Suburban Seniority Investigation (NISSIN) Project using a randomly drawn sub-cohort of 697 subjects (351 men and 346 women; mean age 64.5 [standard deviation, 0.5] years) among whom we compared cases of all-cause death (n = 269) and cancer death (n = 149) during a mean follow-up duration of 10.8 (standard deviation, 3.7) years. Associations between APN and mortality were assessed using weighted Cox regression analyses.

resultsWe observed significant positive associations between the APN concentration and cancer death in the first and third APN tertiles compared with the second APN tertile (hazard ratio [HR]

conclusionPlasma APN and cancer mortality have a significant relationship among community-dwelling elderly people, which warrants further study.

Indexed as

AdiponectinAgedCause of DeathCohort StudiesFemaleHumansIndependent LivingJapanMaleMiddle AgedNeoplasmsAdiponectinadiponectincancer mortalitycase-cohort studycommunity-dwelling elderly

Identifiers

PMID29576602
PMCPMC6048298
OpenAlexW2790461430

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.