ArticleCurrent biology : CB2018
Host-Polarized Cell Growth in Animal Symbionts.
Article in Current biology : CB, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
16 citing papers in PubMed, 34 citations in OpenAlex.
- Article
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- Evolution of longitudinal division in multicellular bacteria of the Neisseriaceae family.Nature communications · 2022Article
- The Longitudinal Dividing BacteriumInternational journal of molecular sciences · 2022Article
- FtsZ-mediated fission of a cuboid bacterial symbiont.iScience · 2022Article
- Anaerobic Sulfur Oxidation Underlies Adaptation of a Chemosynthetic Symbiont to Oxic-Anoxic Interfaces.mSystems · 2021Article
- Article
- PBP4 Is Likely Involved in Cell Division of the Longitudinally Dividing BacteriumAntibiotics (Basel, Switzerland) · 2021Article
- The Ethanologenic Bacterium Zymomonas mobilis Divides Asymmetrically and Exhibits Heterogeneity in DNA Content.Applied and environmental microbiology · 2021Article
- Ectopic positioning of the cell division plane is associated with single amino acid substitutions in the FtsZ-recruiting SsgB inOpen biology · 2021Article
- Efficient Detection of Longitudinal Bacteria Fission Using Transfer Learning in Deep Neural Networks.Frontiers in microbiology · 2021Article
- Insights into the Structure, Function, and Dynamics of the Bacterial Cytokinetic FtsZ-Ring.Annual review of biophysics · 2020Review
- Non-essentiality of canonical cell division genes in the planctomycete Planctopirus limnophila.Scientific reports · 2020Article
- Mechanisms of Incorporation for D-Amino Acid Probes That Target Peptidoglycan Biosynthesis.ACS chemical biology · 2019Article
- Article
- Is Longitudinal Division in Rod-Shaped Bacteria a Matter of Swapping Axis?Frontiers in microbiology · 2018Review
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Authors and funding
11 authors at 4 institutions in 3 countries.
Funding
Abstract
To determine the fundamentals of cell growth, we must extend cell biological studies to non-model organisms. Here, we investigated the growth modes of the only two rods known to widen instead of elongating, Candidatus Thiosymbion oneisti and Thiosymbion hypermnestrae. These bacteria are attached by one pole to the surface of their respective nematode hosts. By incubating live Ca. T. oneisti and T. hypermnestrae with a peptidoglycan metabolic probe, we observed that the insertion of new cell wall starts at the poles and proceeds inward, concomitantly with FtsZ-based membrane constriction. Remarkably, in Ca. T. hypermnestrae, the proximal, animal-attached pole grows before the distal, free pole, indicating that the peptidoglycan synthesis machinery is host oriented. Immunostaining of the symbionts with an antibody against the actin homolog MreB revealed that it was arranged medially-that is, parallel to the cell long axis-throughout the symbiont life cycle. Given that depolymerization of MreB abolished newly synthesized peptidoglycan insertion and impaired divisome assembly, we conclude that MreB function is required for symbiont widening and division. In conclusion, our data invoke a reassessment of the localization and function of the bacterial actin homolog.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.