ArticleThe American journal of emergency medicine2018
Mortality outcomes based on ED qSOFA score and HIV status in a developing low income country.
Article in The American journal of emergency medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed.
- Unsupervised Classification of the Host Response Identifies Dominant Pathobiological Signatures of Sepsis in Sub-Saharan Africa.American journal of respiratory and critical care medicine · 2025Article
- The Global Burden of Sepsis and Septic Shock.Epidemiologia (Basel, Switzerland) · 2024Review
- Combining C-reactive protein and quick sequential organ failure assessment (qSOFA) to improve prognostic accuracy for sepsis and mortality in adult inpatients: A systematic review.Health science reports · 2023Article
- Article
- A comparison of different scores for diagnosis and mortality prediction of adults with sepsis in Low-and-MiddleEClinicalMedicine · 2021Article
- Predicting mortality in adults with suspected infection in a Rwandan hospital: an evaluation of the adapted MEWS, qSOFA and UVA scores.BMJ open · 2021Article
- Performance of Prognostication Scores for Mortality in Injured Patients in Rwanda.The western journal of emergency medicine · 2021Article
- Emergency medicine matters: epidemiology of medical pathology and changes in patient outcomes after implementation of a post-graduate training program at a Tertiary Teaching Hospital in Kigali, Rwanda.International journal of emergency medicine · 2021Article
- Observational
- Profile of presentation of HIV-positive patients to an emergency department in Johannesburg, South Africa.Southern African journal of HIV medicine · 2021Article
- Prognostic value of the Quick Sepsis-related Organ Failure Assessment (qSOFA) score among critically ill medical and surgical patients with suspected infection in a resource-limited setting.African journal of thoracic and critical care medicine · 2021Article
- The Prevalence and Outcomes of Sepsis in Adult Patients in Two Hospitals in Malawi.The American journal of tropical medicine and hygiene · 2020Article
- Funding sources for research: A research primer for low- and middle-income countries.African journal of emergency medicine : Revue africaine de la medecine d'urgence · 2020Article
- The Combined SIRS + qSOFA (qSIRS) Score is More Accurate Than qSOFA Alone in Predicting Mortality in Patients with Surgical Sepsis in an LMIC Emergency Department.World journal of surgery · 2020Article
- Predictive Validity of the qSOFA Score for Sepsis in Adults with Community-Onset Staphylococcal Infection in Thailand.Journal of clinical medicine · 2019Article
- Musculoskeletal Injuries and Outcomes Pre- and Post- Emergency Medicine Training Program.The western journal of emergency medicine · 2019Observational
- Impact of emergency medicine training implementation on mortality outcomes in Kigali, Rwanda: An interrupted time-series study.African journal of emergency medicine : Revue africaine de la medecine d'urgence · 2019Article
- A Prospective Comparison of Quick Sequential Organ Failure Assessment, Systemic Inflammatory Response Syndrome Criteria, Universal Vital Assessment, and Modified Early Warning Score to Predict Mortality in Patients with Suspected Infection in Gabon.The American journal of tropical medicine and hygiene · 2019Observational
- Clinical emergency care research in low-income and middle-income countries: opportunities and challenges.BMJ global health · 2019Review
- Article
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Authors and funding
10 authors.
Funding
Abstract
objectiveTo evaluate the utility of the quick Sepsis-related Organ Failure Assessment (qSOFA) score to predict risks for emergency department (ED) and hospital mortality among patients in a sub-Saharan Africa (SSA) setting.
methodsThis retrospective cohort study was carried out at a tertiary-care hospital, in Kigali, Rwanda and included patients ≥15years, presenting for ED care during 2013 with an infectious disease (ID). ED and overall hospital mortality were evaluated using multivariable regression, with qSOFA scores as the primary predictor (reference: qSOFA=0), to yield adjusted relative risks (aRR) with 95% confidence intervals (CI). Analyses were performed for the overall population and stratified by HIV status.
resultsAmong 15,748 cases, 760 met inclusion (HIV infected 197). The most common diagnoses were malaria and intra-abdominal infections. Prevalence of ED and hospital mortality were 12.5% and 25.4% respectively. In the overall population, ED mortality aRR was 4.8 (95% CI 1.9-12.0) for qSOFA scores equal to 1 and 7.8 (95% CI 3.1-19.7) for qSOFA scores ≥2. The aRR for hospital mortality in the overall cohort was 2.6 (95% 1.6-4.1) for qSOFA scores equal to 1 and 3.8 (95% 2.4-6.0) for qSOFA scores ≥2. For HIV infected cases, although proportional mortality increased with greater qSOFA score, statistically significant risk differences were not identified.
conclusionThe qSOFA score provided risk stratification for both ED and hospital mortality outcomes in the setting studied, indicating utility in sepsis care in SSA, however, further prospective study in high-burden HIV populations is needed.
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