Observational studyBritish journal of anaesthesia2018
Pain after orthopaedic surgery: differences in patient reported outcomes in the United States vs internationally. An observational study from the PAIN OUT dataset.
Observational study in British journal of anaesthesia, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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Who cites it
20 citing papers in PubMed, 44 citations in OpenAlex.
- Optimizing recovery An opioid-free pathway for reconstructive urology.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2026Article
- The information that patients, their families, and medical staff wish to know about postoperative pain and its management. Results of the survey after mixed surgical procedures.Frontiers in pain research (Lausanne, Switzerland) · 2026Article
- North American and European practices for opioid-sparing and opioid-free anaesthesia: a cross-sectional survey.BJA open · 2025Article
- Article
- Article
- Early Outcomes of Orthopedic Pre-surgical Patients Enrolled in an Intensive, Interprofessional Lifestyle Medicine Program to Optimize Health.American journal of lifestyle medicine · 2024Article
- Pain Control Associated With Gabapentinoid Prescription After Elective Total Knee Arthroplasty.The Journal of arthroplasty · 2024Article
- A random forest algorithm-based prediction model for moderate to severe acute postoperative pain after orthopedic surgery under general anesthesia.BMC anesthesiology · 2023Article
- Postoperative pain-related outcomes and perioperative pain management in China: a population-based study.The Lancet regional health. Western Pacific · 2023Article
- Evaluating the Use of PROMs in Paediatric Orthopaedic Registries.Children (Basel, Switzerland) · 2023Review
- Managing Post-Operative Pain in Orthopedic Patients: An International Comparison.Kansas journal of medicine · 2023Article
- Positive Association between Peri-Surgical Opioid Exposure and Post-Discharge Opioid-Related Outcomes.Healthcare (Basel, Switzerland) · 2022Article
- Observational
- How orthopedic surgeons view open label placebo pills: Ethical and effective, but opposed to personal use.Journal of psychosomatic research · 2021Article
- The use of 2-octyl cyanoacrylate as an adjuvant to wound closure in total knee arthroplasty.Archives of orthopaedic and trauma surgery · 2021Article
- Opioid Consumption After Arthroscopic Meniscal Procedures and Anterior Cruciate Ligament Reconstruction.Orthopaedic journal of sports medicine · 2020Article
- Review of the Transitional Pain Service as a method of postoperative opioid weaning and a service aimed at minimizing the risk of chronic post-surgical pain.Anaesthesiology intensive therapy · 2020Review
- Confirmatory factor analysis of the International Pain Outcome questionnaire in surgery.Pain reportsArticle
- Article
- The Effect of Reducing the Fasting Time on Postoperative Pain in Orthopaedic Patients: A Randomized Controlled Trial.Iranian journal of nursing and midwifery researchArticle
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundA previous PAIN OUT study found that American orthopaedic-surgical patients rated 'worst pain' higher than did similar European patients. This study aims to confirm these findings in a larger, international patient sample, explore whether risk factors for greater postoperative pain exist disproportionately in the American population, and confirm the findings for one procedure.
methodsSurveyors collected patient reported outcomes (PROs) and perioperative pain management practices using PAIN OUT methodology. Most PROs used 11-point numerical rating scales (0=null, 10=worst possible). Risk factors included: female gender, younger age, high BMI, chronic pain, and opioid use before surgery. Initial analysis used a mixed patient cohort. A secondary analysis used only patients undergoing total knee replacement (TKR). Inference was based primarily on effect size using Cohen's d.
results13,770 patients in 13 European and non-European countries (international ) and 564 patients from the United States (US) contributed data on the 1st postoperative day. Three of 11 PROs differed between the cohorts: 'worst pain' {US 7.5 (2.5) vs international 5.6 (2.8); d=0.66 [confidence interval (CI) 0.58-0.75]}; proportion 'receiving information about treatment options' [US 0.86 vs international 0.66; d=0.53 (CI 0.39-0.66)]; reporting adverse effects and their severity [US 0.87 vs international 0.73; d=0.52 (CI 0.38-0.66)]. Risk factors did not differ between the two cohorts. PROs and management patterns in TKR patients were similar to the mixed cohort.
conclusionsThree PROs differed between international and US patients, with higher 'worst pain' for US patients. Neither risk factors, nor patient mix accounted for the observed differences for 'worst pain'. CLINICAL
trial registrationNCT 02083835.
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