Evidence map›Paper›PMID 29575784›Full record

ArticleObesity (Silver Spring, Md.)2018

Accumulating Data to Optimally Predict Obesity Treatment (ADOPT): Recommendations from the Biological Domain.

Michael Rosenbaum, Tanya Agurs-Collins, Molly S Bray, Kevin D Hall, Mark Hopkins, Maren Laughlin, Paul S MacLean, Padma Maruvada, Cary R Savage, Dana M Small and 1 more

Abstract read
In one paragraph

Article in Obesity (Silver Spring, Md.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Guideline
  2. Article
  3. Review
  4. Article
  5. Climate Change and Obesity.Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme · 2021
    Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Good practice in food-related neuroimaging.The American journal of clinical nutrition · 2019
    Article
  16. Article
  17. Article
  18. Precision medicine in adult and pediatric obesity: a clinical perspective.Therapeutic advances in endocrinology and metabolism · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Michael RosenbaumColumbia University, Vagelos College of Physicians & Surgeons, New York, New York, USA.ORCID 0000-0002-8908-9448
Tanya Agurs-CollinsNational Cancer Institute, National Institutes of Health, Rockville, Maryland, USA.
Molly S BrayDepartment of Nutritional Sciences, University of Texas at Austin, Austin, Texas, USA.
Kevin D HallNational Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, USA.ORCID 0000-0003-4062-3133
Mark HopkinsSchool of Food Science and Nutrition, University of Leeds, Leeds, England.
Maren LaughlinNational Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, USA.
Paul S MacLeanSchool of Medicine, University of Colorado School of Medicine, Aurora, Colorado, USA.
Padma MaruvadaSchool of Medicine, University of Colorado School of Medicine, Aurora, Colorado, USA.
Cary R SavageCenter for Brain, Biology and Behavior, Department of Psychology, University of Nebraska, Lincoln, Nebraska, USA.
Dana M SmallYale University Medical School, New Haven, Connecticut, USA.
Luke StoeckelNational Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, USA.

Funding

RESEARCH TRAININGP30DK026687 · NIDDK · ST. LUKE'S-ROOSEVELT INST FOR HLTH SCIS · PI Anthony W Ferrante, DYMPNA GALLAGHER · 1986 to 2026
$33.0M
Sex Hormones Differentially Regulate Production of Distinct Adipocyte PopulationP50HD073063 · NICHD · UNIVERSITY OF COLORADO DENVER · PI KOHRT, WENDY M · 2012 to 2017
$5.7M
Leptin in Human Energy and Neuroendocrine HomeostasisR01DK064773 · NIDDK · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI LEIBEL, RUDOLPH L · 2003 to 2013
$3.3M
Functional imaging and eating behavior among FTO genotypes in pre-obese childrenR01DK097399 · NIDDK · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MAYER, LAUREL ES, ROSENBAUM, MICHAEL · 2013 to 2017
$2.9M
NICHD NIH HHS P50 HD073063NIDDK NIH HHS P30 DK026687NIDDK NIH HHS R01 DK064773NIDDK NIH HHS R01 DK097399
6 · The paper itself

Abstract

backgroundThe responses to behavioral, pharmacological, or surgical obesity treatments are highly individualized. The Accumulating Data to Optimally Predict obesity Treatment (ADOPT) project provides a framework for how obesity researchers, working collectively, can generate the evidence base needed to guide the development of tailored, and potentially more effective, strategies for obesity treatment.

objectivesThe objective of the ADOPT biological domain subgroup is to create a list of high-priority biological measures for weight-loss studies that will advance the understanding of individual variability in response to adult obesity treatments. This list includes measures of body composition, energy homeostasis (energy intake and output), brain structure and function, and biomarkers, as well as biobanking procedures, which could feasibly be included in most, if not all, studies of obesity treatment. The recommended high-priority measures are selected to balance needs for sensitivity, specificity, and/or comprehensiveness with feasibility to achieve a commonality of usage and increase the breadth and impact of obesity research. SIGNIFICANCE: The accumulation of data on key biological factors, along with behavioral, psychosocial, and environmental factors, can generate a more precise description of the interplay and synergy among them and their impact on treatment responses, which can ultimately inform the design and delivery of effective, tailored obesity treatments.

Indexed as

Biological Specimen BanksBiomarkersBody CompositionBrainEnergy IntakeHumansObesityWeight LossBiomarkers

Identifiers

PMID29575784
PMCPMC6945498

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.